Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
Alpsoy 2002: high rate of adverse events including alopecia, leukopenia, and diarrhoea; 18 of 23 patients in the treatment arm experienced mild flu-like symptoms.
1 study · 50 participants
GRADE not reported
Adverse effects Beta‐estradiol patch dose 0.10 mg/day · women with hot flushes
Transdermal beta‐estradiol patch may leads to higher adverse effects Beta‐estradiol patch dose 0.10 mg/day compared with placebo (low certainty).
1 finding from 1 review
Adverse effects (side effects; treatment withdrawals) · Patients with radiation-induced salivary gland dysfunction
1 finding from 1 review
Johnson 1993 (5 mg tds): sweating 37%, headache 15%, urinary frequency 14%, vasodilatation 12%, dizziness 10%, dyspepsia 10%, nausea 8%, asthenia 8%, diarrhoea 5%; 6% withdrew at 5 mg tds and 29% at 10 mg tds. LeVeque…
2 studies · 278 participants
GRADE not reported
Adverse effect: fatigue · patients with drug‐resistant epilepsy
Flunarizine showed no clear difference in adverse effects ‐ Fatigue No of patients with fatigue compared with placebo (high certainty).
1 finding from 1 review
Number with adverse effects ‐ Systemic administration · patients with urinary incontinence in post‐menopausal women
Oestrogen may leads to higher number with adverse effects ‐ Systemic administration compared with placebo or no treatment (low certainty).
1 finding from 1 review
Adverse effect: extrapyramidal symptoms ‐ not reported · patients with sexual dysfunction due to antipsychotic drug therapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects: moderate to severe Infusion reactions · SSNS in children
Rituximab may leads to higher adverse effects: moderate to severe Infusion reactions compared with placebo or control (low certainty).
1 finding from 1 review
Adverse effects: suicidal thoughts (events) · people in the prodromal stage of psychosis
It is very uncertain whether group A: amino acids changes adverse effects: suicidal thoughts Short‐term (events) compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects after treatment initiation: infections · children diagnosed with Kawasaki disease
TNF‐α blockers intervention showed no clear difference in adverse effects after treatment initiation: infections compared with placebo or additional treatment (low certainty).
1 finding from 1 review
Adverse events: Vomiting · patients with drug‐resistant epilepsy
Flunarizine showed no clear difference in adverse effects ‐ Vomiting No of patients with vomiting compared with placebo (high certainty).
1 finding from 1 review
Serious adverse effects (bleeding or seizures) · adults with tinnitus
1 finding from 1 review
Diarrhoea · women with obesity during pregnancy
Metformin leads to higher adverse effects associated with the treatment: diarrhoea compared with placebo (high certainty).
1 finding from 1 review
Adverse effects: Metabolic ‐ weight change (medium term) · patients with schizophrenia
1 finding from 1 review
Adverse effects: Extrapyramidal symptoms (Simpson‐Angus) · patients with sexual dysfunction due to antipsychotic drug therapy
1 finding from 1 review
Gastrointestinal adverse events · residents of long‐term care (≥ 65 years) with pressure ulcers; inpatients with pressure ulcers
It is very uncertain whether summary of findings table ‐ Protein, arginine, zinc and antioxidants changes side effects: at least one adverse gastrointestinal event compared with standard diet or placebo (very low certainty).
1 finding from 1 review
Adverse effects requiring withdrawal/discontinuation of study medication · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in side effects or other adverse events requiring withdrawal compared with placebo (placebo solution/mouthwash) (moderate certainty).
1 finding from 1 review
Frequency of adverse effects ‐ dizziness ( · patients with drug‐resistant epilepsy
Flunarizine showed no clear difference in adverse effects ‐ Dizziness No of patients with dizziness compared with placebo (high certainty).
1 finding from 1 review
Ataxia · people with focal epilepsy
Zonisamide may leads to higher adverse effects: ataxia (whole treatment period; any dose) compared with placebo (low certainty).
1 finding from 1 review
Nausea · people with focal epilepsy
Zonisamide probably leads to higher adverse effects: nausea (whole treatment period; any dose) compared with placebo (moderate certainty).
1 finding from 1 review
Adverse effects (number of participants who had the event) · People with American cutaneous leishmaniasis
1 finding from 1 review