Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

536 questions · 579 findings · 94 reviews

No studies found 151 · 26.1%GRADE not reported 52 · 9%Very low 182 · 31.4%Low 120 · 20.7%Moderate 52 · 9%High 22 · 3.8%

Intervention vs any comparison

Mortality ‐ Topical povidone iodine gel versus no topical povidone iodine gel · patients undergoing liver resections

It is very uncertain whether intervention changes mortality ‐ Topical povidone iodine gel versus no topical povidone… compared with comparison (very low certainty).

1 finding from 1 review

Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs usual practice

Dental caries prevalence measured by dmft or DMFT/S score greater than one · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)

School-based interventions may reduce the prevalence of dental caries (RR 0.70, favouring intervention), but the certainty of evidence is very low.

3 findings from 1 review

An intervention delivered at one time point vs The same intervention delivered at a different time point

Outcome not reported · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Health‐related quality of life (physical) · adults with acute acromioclavicular dislocation of the shouldera
1 finding from 1 review

Multi‐component intervention vs other treatments/routine care

Number experiencing adverse effects · the management of chronic obstructive pulmonary disease

It is very uncertain whether multi‐component intervention changes adverse events: number of people experiencing an AE compared with other intervention or routine, usual care or control treatment (very low certainty).

1 finding from 1 review

Multi‐component intervention vs other treatments/routine care

Number of participants experiencing any serious adverse events · the management of chronic obstructive pulmonary disease

Multi‐component intervention showed no clear difference in adverse events: number of people experiencing a serious adverse event compared with other intervention or routine, usual care or control treatment (low certainty).

1 finding from 1 review

Multi‐component intervention vs no intervention

Proportion of participants with low back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with low back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Multi‐component intervention vs no intervention

Proportion of participants with upper back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with upper back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review