Cochrane · systematic review · CD013384

Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other long‐term condition: a mixed methods review

Dennett, EJ, Janjua, S, Stovold, E, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
7
No studies
7
Included studies
NR
No studies 7 · 50%Ungraded 0 · 0%Very low 3 · 21.4%Low 4 · 28.6%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Intervention compared to usual care for COPD and at least one other long‐term condition

Population: COPD and at least one other long‐term condition
7 questions
OutcomeEffectEvidenceStatus / GRADE
Outcome domain
Intervention vs usual care
no estimate extractedNRNo studies
Quality of life ‐ SGRQ totalScale from: 0 to 100 (lower scores better) Â
Intervention vs usual care
no estimate extracted1 study · 70 participantsLow
Downgraded: risk of bias, imprecision
Quality of life ‐ CAT total Scale from 0 to 40 (lower scores better) Â
Intervention vs usual care
no estimate extracted1 study · 77 participantsLow
Downgraded: risk of bias, imprecision
Exacerbations ‐ number of people experiencing one or more Â
Intervention vs usual care
OR 1.09 [0.75, 1.57]1 study · 470 participantsVery low
Downgraded: risk of bias, imprecision
Functional status‐6MWD (metres) Â
Intervention vs usual care
no estimate extracted2 studies · 100 participantsLow
Downgraded: risk of bias, imprecision
All‐cause hospital admissions ‐ people experiencing one or more Â
Intervention vs usual care
OR 0.91 [0.55, 1.5]1 study · 312 participantsLow
Downgraded: risk of bias
All‐cause mortality (deaths) Â
Intervention vs usual care
OR 0.55 [0.23, 1.35]2 studies · 177 participantsVery low
Downgraded: risk of bias, imprecision

Intervention compared to active comparison for COPD and at least one other long‐term condition

Population: COPD and at least one other long‐term condition
7 questions
OutcomeEffectEvidenceStatus / GRADE
Outcome domain
Intervention vs active comparison
no estimate extractedNRNo studies
Quality of life ‐ SGRQ totalÂ
Intervention vs active comparison
no estimate extractedNRNo studies
Quality of life ‐ CAT totalÂ
Intervention vs active comparison
no estimate extractedNRNo studies
ExacerbationsÂ
Intervention vs active comparison
no estimate extractedNRNo studies
Functional status ‐ 6MWD (metres)
Intervention vs active comparison
no estimate extracted1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision
All‐cause hospital admissionsÂ
Intervention vs active comparison
no estimate extractedNRNo studies
All‐cause mortalityÂ
Intervention vs active comparison
no estimate extractedNRNo studies