Mucositis eradicated · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Chlorhexidine mouthwash showed no clear difference in mucositis eradicated compared with salt and soda mouthwash; GRADE not reported.
1 finding from 1 review
Time to heal mucositis (days) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Chlorhexidine mouthwash showed no clear difference in time to heal mucositis (days) compared with salt and soda mouthwash; GRADE not reported.
1 finding from 1 review
Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Chlorhexidine mouthwash showed no clear difference in average pain scores (0-100 VAS) compared with salt and soda mouthwash; GRADE not reported.
1 finding from 1 review
Caries increment in permanent teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Dental caries: dmfs increment (primary teeth) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine rinse (0.2%) pre- and post-extraction showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%) post-extraction only; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine 0.2% socket irrigation (monoject syringe) led to lower presence of dry socket compared with chlorhexidine 0.2% mouthrinse; GRADE not reported.
1 finding from 1 review
Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
GBS pneumonia within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes GBS pneumonia within the first seven days of life compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Neonatal colonization with GBS within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes neonatal colonization with GBS within the first seven days of life compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Neonatal mortality due to early‐onset GBS infection · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
1 finding from 1 review
Adverse (mild) effects in the mother · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes adverse (mild) effects in the mother compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Adverse (mild) effects in the neonate · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants
1 finding from 1 review
Hospital‐acquired infections Data collected during ICU stay · critically ill patients
1 finding from 1 review
Mortality (ICU, hospital) (days) · critically ill patients
It is very uncertain whether bathing of the critically ill with chlorhexidine changes mortality Data collected (where reported) in hospital, in the ICU,… compared with bathing with soap and water or non‐antimicrobial washcloths (very low certainty).
1 finding from 1 review
Duration of ICU stay · critically ill patients
1 finding from 1 review
OLT and VSC scores · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
1% chlorhexidine + 1% thymol varnish may not differ from 38% SDF + potassium iodide solution (applied annually) for arrest or reversal of root carious lesions (RR 0.71, 95% CI 0.11 to 4.45; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
1% chlorhexidine + 1% thymol varnish may not differ from 5% NaF varnish for arrest or reversal of root carious lesions (RR 0.57, 95% CI 0.04 to 8.69; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
1% chlorhexidine + 1% thymol varnish may not differ from no treatment for arrest or reversal of root carious lesions (RR 1.67, 95% CI 0.44 to 6.31; very low certainty).
1 finding from 1 review