Question · asked by 1 review

1% chlorhexidine + 1% thymol varnish vs no treatment: Arrest or reversal of noncavitated and cavitated root carious lesions

Population
Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
Intervention
1% chlorhexidine + 1% thymol varnish
Comparison
no treatment
Outcome
Arrest or reversal of noncavitated and cavitated root carious lesions

1% chlorhexidine + 1% thymol varnish may not differ from no treatment for arrest or reversal of root carious lesions (RR 1.67, 95% CI 0.44 to 6.31; very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
1% chlorhexidine + 1% thymol varnish vs No treatment
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces… · 3-12 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs)
1% chlorhexidine + 1% thymol varnish may not differ from no treatment for arrest or reversal of root carious lesions (RR 1.67, 95% CI 0.44 to 6.31; very low certainty).
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes
RR 1.67 [0.44, 6.31]7 studies · 1304 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis.
2019 All outcomes
June 201754Critically Low / Critically Low

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.