Question · asked by 1 review
Chlorhexidine varnish (10% and 40%) vs placebo or no treatment: Caries increment in permanent teeth
- Population
- Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or primary dentition, moderate to high caries risk
- Intervention
- Chlorhexidine varnish (10% and 40%)
- Comparison
- placebo or no treatment
- Outcome
- Caries increment in permanent teeth
It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine varnish (10% and 40%) vs Placebo or no treatment Caries increment in permanent dentition (DMFS; higher values indicate greater caries) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with… · 30 to 36 months, permanent dentition It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty). Chlorhexidine treatment for the prevention of dental caries in children and adolescents (2015) · Cochrane All outcomes | MD 0.53 [-0.47, 1.53] | 2 studies · 690 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Chlorhexidine treatment for the prevention of dental caries in children and adolescents 2015 · Cochrane All outcomes | 2015-02 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.