Cochrane · systematic review · CD012248
Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection
Lewis, SR, Schofield‐Robinson, OJ, Rhodes, S, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Bathing of the critically ill with chlorhexidine versus bathing with soap and water or non‐antimicrobial washcloths for the prevention of hospital acquired infections
Population: people who are critically ill
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Hospital‐acquired infections Data collected during ICU stay Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths | no estimate extracted | 8 studies · 21924 participants | Very low Downgraded: risk of bias, inconsistency, indirectness |
Mortality Data collected (where reported) in hospital, in the ICU, and at 48 hours Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths | OR 0.87 [0.76, 0.99] | 6 studies · 15798 participants | Very low Downgraded: risk of bias, inconsistency, indirectness |
Length of stay in the ICU Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths | no estimate extracted | 6 studies · 18570 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Adverse effects: skin reactions. Reported as attributable to chlorhexidine or soap and water. Data collected during ICU stay Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths | no estimate extracted | 5 studies · 6365 participants | Very low Downgraded: risk of bias, imprecision, indirectness |