Neonatal death (baby born alive at any gestation and dies within 28 days) · women in labor with management of intra‐amniotic infection
It is very uncertain whether antibiotics changes neonatal deaths compared with antibiotics (very low certainty).
1 finding from 1 review
Neonatal sepsis · women in labor with management of intra‐amniotic infection
Antibiotics showed no clear difference in neonatal sepsis compared with antibiotics (low certainty).
1 finding from 1 review
Respiratory distress syndrome · women in labor with management of intra‐amniotic infection
Antibiotics showed no clear difference in respiratory distress syndrome compared with antibiotics (low certainty).
1 finding from 1 review
Maternal postpartum hospital stay (days) · women in labor with management of intra‐amniotic infection
1 finding from 1 review
Postpartum readmission for endometritis · women in labor with management of intra‐amniotic infection
1 finding from 1 review
Endometritis/Failure treatment · women in labor with management of intra‐amniotic infection
Antibiotics showed no clear difference in treatment failure (endometritis) compared with antibiotics (low certainty).
1 finding from 1 review
Need for additional antibiotic therapy · women with management of intra‐amniotic infection
1 finding from 1 review
Surgical complications ‐ wound infection · patients with colorectal surgery
Antibiotic leads to lower surgical wound infection (SWI) compared with no antibiotic/placebo (high certainty).
1 finding from 1 review
Adverse effects of antibiotics · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in treatment harms (adverse events or side effects associated with… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
Antibiotic resistance · people with bronchiectasis
14 days on/off antibiotic regimen showed no clear difference in antibiotic resistance compared with 28 days on/off antibiotic regimen (moderate certainty).
1 finding from 1 review
OR 1 [0.68, 1.48]
Studies not reported
Moderate
Antibiotic resistance · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
28‐day antibiotic‐free days · hospital‐acquired pneumonia
1 finding from 1 review
Need for additional IV or oral antibiotics · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
It is very uncertain whether summary of findings: Inhaled antibiotics changes need for additional IV or oral antibiotics compared with IV antibiotics (very low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured at 1 to 2 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
Ear pain (otalgia) or discomfort or local irritation · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Hearing ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
Serious complications ‐ mastoid abscess measured at 12 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
It is very uncertain whether systemic antibiotics changes serious complications ‐ mastoid abscess measured at 12 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).
1 finding from 1 review
Suspected ototoxicity · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Active trachoma · people (any age) with active trachoma
Antibiotic may leads to lower active trachoma Clinical assessment: active trachoma defined as TF,… compared with control (low certainty).
1 finding from 1 review