Question · asked by 1 review

Antibiotics vs antibiotics alone: Neonatal death (baby born alive at any gestation and dies within 28 days)

Population
women in labor with management of intra‐amniotic infection
Intervention
Antibiotics
Comparison
antibiotics alone
Outcome
Neonatal death (baby born alive at any gestation and dies within 28 days)

It is very uncertain whether antibiotics changes neonatal deaths compared with antibiotics (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Antibiotics vs antibiotics
Neonatal deaths · women in labor with management of intra‐amniotic infection
It is very uncertain whether antibiotics changes neonatal deaths compared with antibiotics (very low certainty).
Antibiotic regimens for management of intra‐amniotic infection (2014) · Cochrane Headline outcomes only
RR 1.39 [0.24, 8.06]1 study · 133 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotic regimens for management of intra‐amniotic infection
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.