Cochrane · systematic review · CD001181
Antimicrobial prophylaxis for colorectal surgery
Nelson, RL, Gladman, E, Barbateskovic, M · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 3 · 100%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotic versus no antibiotic/placebo for colorectal surgery
Population: patients undergoing colorectal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Surgical wound infection (SWI) Antibiotic vs no antibiotic/placebo | RR 0.34 [0.28, 0.41] | 30 studies · 2455 participants | High |
Combined oral and intravenous compared to oral or intravenous alone for colorectal surgery
Population: colorectal surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Surgical wound infection: oral + iv versus iv alone Combined oral and intravenous vs oral or intravenous alone | RR 0.55 [0.43, 0.71] | 15 studies · 2929 participants | High |
Surgical wound infection: combined oral and iv versus oral alone Combined oral and intravenous vs oral or intravenous alone | RR 0.52 [0.35, 0.76] | 9 studies · 1880 participants | High |