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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

249 questions in 68 reviews · Airways

current versions
No studies 249 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Remote monitoring plus usual care vs usual care
Quality of life · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Dyspnoea symptoms · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
No evidence identified · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Multi‐component interventions (with telehealth as a component of care) vs usual care
Mortality · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring plus usual care vs usual care
Dyspnoea symptoms · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Remote monitoring plus usual care vs usual care
No evidence identified · people with chronic obstructive pulmonary disease
Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs usual care
Outcome domain · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs active comparison
Quality of life ‐ CAT total · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs active comparison
Exacerbations · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs active comparison
All‐cause hospital admissions · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs active comparison
All‐cause mortality · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs active comparison
Outcome domain · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention vs active comparison
Quality of life ‐ SGRQ total · COPD and at least one other long‐term condition
Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one… (2021) · Cochrane
no estimate extractedNRNo studies
Individual level interventions vs control
Respiratory exacerbations · healthy individuals and those with a pre‐existing health condition
Individual‐level interventions to reduce personal exposure to outdoor air pollution and their effects on… (2021) · Cochrane
no estimate extractedNRNo studies
Individual level interventions vs control
Quality of life · healthy individuals and those with a pre‐existing health condition
Individual‐level interventions to reduce personal exposure to outdoor air pollution and their effects on… (2021) · Cochrane
no estimate extractedNRNo studies
Individual level interventions vs control
Serious adverse events · healthy individuals and those with a pre‐existing health condition
Individual‐level interventions to reduce personal exposure to outdoor air pollution and their effects on… (2021) · Cochrane
no estimate extractedNRNo studies
Supervised maintenance programme following pulmonary rehabilitation vs usual care
Outcomes · chronic obstructive pulmonary disease
Supervised maintenance programmes following pulmonary rehabilitation compared to usual care for chronic… (2021) · Cochrane
no estimate extractedNRNo studies
Breathing exercises vs inactive control
Inpatient hospitalisation episodes · adults with asthma
Breathing exercises for adults with asthma (2020) · Cochrane
no estimate extractedNRNo studies
Breathing exercises vs inactive control
Days off work · adults with asthma
Breathing exercises for adults with asthma (2020) · Cochrane
no estimate extractedNRNo studies
Titrated oxygen therapy vs high‐flow oxygen therapy
Quality of life ‐ not measured · adults with acute exacerbations of chronic obstructive pulmonary disease
Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
Titrated oxygen therapy vs high‐flow oxygen therapy
Lung function ‐ not measured · adults with acute exacerbations of chronic obstructive pulmonary disease
Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
Titrated oxygen therapy vs high‐flow oxygen therapy
Dyspnoea score ‐ not measured · adults with acute exacerbations of chronic obstructive pulmonary disease
Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
Montelukast vs placebo
Serious adverse events (N experiencing event) · obstructive sleep apnoea in children
Anti‐inflammatory medications for obstructive sleep apnoea in children (2020) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Serious adverse events (N experiencing events) · obstructive sleep apnoea in children
Anti‐inflammatory medications for obstructive sleep apnoea in children (2020) · Cochrane
no estimate extractedNRNo studies
Sublingual immunotherapy vs control
Quality of life · adults and children with asthma
Sublingual immunotherapy for asthma (2020) · Cochrane
no estimate extractedNRNo studies
PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease
Pneumonia and other serious adverse events · chronic obstructive pulmonary disease
Proton pump inhibitors for chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease
Quality of life · chronic obstructive pulmonary disease
Proton pump inhibitors for chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease
Lung function indices · chronic obstructive pulmonary disease
Proton pump inhibitors for chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease
Disease‐specific adverse events · chronic obstructive pulmonary disease
Proton pump inhibitors for chronic obstructive pulmonary disease (2020) · Cochrane
no estimate extractedNRNo studies
Atorvastatin vs placebo
Asthma exacerbations requiring hospitalisation or a course of steroids · people with asthma
Statins for asthma (2020) · Cochrane
no estimate extractedNRNo studies
Atorvastatin vs placebo
Health‐related quality of life · people with asthma
Statins for asthma (2020) · Cochrane
no estimate extractedNRNo studies
Atorvastatin vs placebo
Serious adverse events or adverse events · people with asthma
Statins for asthma (2020) · Cochrane
no estimate extractedNRNo studies
Mucolytic vs placebo
Outcomes* · chronic bronchitis or COPD
Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease (2019) · Cochrane
no estimate extractedNRNo studies
Bi‐PAP vs fixed CPAP
Machine usage assessed by number of participants using machine for 4 or more hours per night ‐ not measured · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
Bi‐PAP vs fixed CPAP
Blood pressure ‐ not measured · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
CPAP with expiratory pressure relief vs fixed CPAP
Machine usage assessed by number of participants using machine for 4 or more hours per night ‐ not measured · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
CPAP with expiratory pressure relief vs fixed CPAP
Blood pressure ‐ not measured · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
Heated humidification + fixed CPAP vs fixed CPAP alone
Machine usage assessed by number of participants using machine for 4 or more hours per night ‐ not measured · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
Heated humidification + fixed CPAP vs fixed CPAP alone
Quality of life · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
Heated humidification + fixed CPAP vs fixed CPAP alone
Blood pressure ‐ not measured · adults with a diagnosis of sleep apnoea
Pressure modification or humidification for improving usage of continuous positive airway pressure machines… (2019) · Cochrane
no estimate extractedNRNo studies
Group 3 Pulmonary hypertension due to lung disease ‐ PDE5i vs placebo
Mortality · people with pulmonary hypertension due to lung disease
Phosphodiesterase 5 inhibitors for pulmonary hypertension (2019) · Cochrane
no estimate extractedNRNo studies
Mixed Pulmonary hypertension group 2 ‐ 4 ‐ PDE5i vs placebo
Mortality · people with pulmonary hypertension group 2 ‐ 4
Phosphodiesterase 5 inhibitors for pulmonary hypertension (2019) · Cochrane
no estimate extractedNRNo studies
Mixed Pulmonary hypertension group 2 ‐ 4 ‐ PDE5i vs placebo
Quality of life · people with pulmonary hypertension group 2 ‐ 4
Phosphodiesterase 5 inhibitors for pulmonary hypertension (2019) · Cochrane
no estimate extractedNRNo studies
Quinolone vs macrolide
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · chronic obstructive pulmonary disease
Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease (2019) · Cochrane
no estimate extractedNRNo studies
Macrolide vs tetracycline
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · chronic obstructive pulmonary disease
Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease (2019) · Cochrane
no estimate extractedNRNo studies
Macrolide+tetracycline vs macrolide
Number of people experiencing one or more exacerbations, Drug resistance/microbial sensitivity (as reported by trialists), including emergence of atypical bacteria, Number of participants colonised with Pseudomonas aeruginosa · chronic obstructive pulmonary disease
Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease (2019) · Cochrane
no estimate extractedNRNo studies
Quinolone vs tetracycline
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · chronic obstructive pulmonary disease
Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease (2019) · Cochrane
no estimate extractedNRNo studies
Influenza vaccine vs placebo
Days disability from respiratory illness · chronic obstructive pulmonary disease (COPD)
Influenza vaccine for chronic obstructive pulmonary disease (COPD) (2018) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs placebo or usual care
ICU/HDU admission ‐ not reported · acute asthma exacerbation
Antibiotics for exacerbations of asthma (2018) · Cochrane
no estimate extractedNRNo studies
Antibiotics vs placebo or usual care
Mortality ‐ not reported · acute asthma exacerbation
Antibiotics for exacerbations of asthma (2018) · Cochrane
no estimate extractedNRNo studies