Cochrane · systematic review · CD005534

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease

Kopsaftis, Z, Carson‐Chahhoud, KV, Austin, MA, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Titrated oxygen therapy compared to high‐flow oxygen therapy for acute exacerbations of chronic obstructive pulmonary disease

Population: adults with acute exacerbations of chronic obstructive pulmonary disease
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality (respiratory‐ related and all‐cause
Titrated oxygen therapy vs high‐flow oxygen therapy
RR 0.22 [0.05, 0.97]1 study · 214 participantsLow
Downgraded: imprecision, indirectness
Arterial blood gas (pH)
Titrated oxygen therapy vs high‐flow oxygen therapy
no estimate extracted1 study · 214 participantsLow
Downgraded: imprecision, indirectness
Ventilation of any type
Titrated oxygen therapy vs high‐flow oxygen therapy
RR 0.67 [0.29, 1.55]1 study · 189 participantsLow
Downgraded: imprecision, indirectness
Length of hospital stay
Titrated oxygen therapy vs high‐flow oxygen therapy
no estimate extracted1 study · 214 participantsLow
Downgraded: imprecision, indirectness
Quality of life ‐ not measured
Titrated oxygen therapy vs high‐flow oxygen therapy
no estimate extractedNRNo studies
Lung function ‐ not measured
Titrated oxygen therapy vs high‐flow oxygen therapy
no estimate extractedNRNo studies
Dyspnoea score ‐ not measured
Titrated oxygen therapy vs high‐flow oxygen therapy
no estimate extractedNRNo studies