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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

135 questions in 34 reviews · Infectious Diseases

current versions
No studies 135 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
RotaTeq vs placebo
Severe all‐cause diarrhoea · children
Vaccines for preventing rotavirus diarrhoea: vaccines in use (2021) · Cochrane
no estimate extractedNRNo studies
Rotavac vs placebo
Severe cases of all‐cause diarrhoea · children
Vaccines for preventing rotavirus diarrhoea: vaccines in use (2021) · Cochrane
no estimate extractedNRNo studies
Xpert Ultra vs Xpert MTB/RIF
Test result · adults with presumptive pulmonary tuberculosis. Participants were unselected, meaning they were not enrolled in a…
Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with… (2021) · Cochrane
no estimate extractedNRNo studies
Xpert Ultra vs Xpert MTB/RIF
Test result · adults with presumptive pulmonary tuberculosis Role: an initial test Index tests: Xpert Ultra and Xpert MTB/RIF…
Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Parasitaemia · malaria in infants
Intermittent preventive treatment for malaria in infants (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severe malaria · malaria in infants
Intermittent preventive treatment for malaria in infants (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Parasitaemia · malaria in infants
Intermittent preventive treatment for malaria in infants (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severe malaria · malaria in infants
Intermittent preventive treatment for malaria in infants (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert Ultra result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert MTB/RIF result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert Ultra result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert MTB/RIF result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert Ultra result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert MTB/RIF result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert MTB/RIF result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Xpert Ultra result
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Index test · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for…
Screening tests for active pulmonary tuberculosis in children (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Estimation (95% Cl) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for…
Screening tests for active pulmonary tuberculosis in children (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Estimations · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for…
Screening tests for active pulmonary tuberculosis in children (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Index test, population · people living with HIV and non‐hospitalized people in high‐risk groups
Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Index test · people in high‐risk groups
Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in… (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adult worm prevalence detected by ultrasound ‐ not measured · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adult worm prevalence detected by ultrasound ‐ not measured · people with lymphatic filariasis or communities where lymphatic filariasis is endemic
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Test result
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
False positives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
True positives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
False negatives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
True negatives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
False positives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Test result
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
True positives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
False negatives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
True negatives
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Test result · HIV‐positive individuals
Abdominal ultrasound for diagnosing abdominal tuberculosis or disseminated tuberculosis with abdominal… (2019) · Cochrane
no estimate extractedNRNo studies
Linezolid vs no linezolid
Serious adverse events · drug‐resistant pulmonary tuberculosis
Linezolid for drug‐resistant pulmonary tuberculosis (2019) · Cochrane
no estimate extractedNRNo studies
Vi polysaccharide vaccine (1 dose) vs control
Serious adverse events · adults and children of 2 years of age and older
Vaccines for preventing typhoid fever (2018) · Cochrane
no estimate extractedNRNo studies
Rifampicin vs doxycycline
Resolution of fever within 5 days · adults with scrub typhus
Antibiotics for treating scrub typhus (2018) · Cochrane
no estimate extractedNRNo studies
Rifampicin vs doxycycline
Serious adverse events · adults with scrub typhus
Antibiotics for treating scrub typhus (2018) · Cochrane
no estimate extractedNRNo studies
Doxycycline vs tetracycline
Resolution of fever within 5 days · adults with scrub typhus
Antibiotics for treating scrub typhus (2018) · Cochrane
no estimate extractedNRNo studies
Doxycycline vs tetracycline
Serious adverse events · adults with scrub typhus
Antibiotics for treating scrub typhus (2018) · Cochrane
no estimate extractedNRNo studies
Resistance testing vs no resistance testing
Quality of life ‐ not reported · HIV‐positive people
Antiretroviral resistance testing in HIV‐positive people (2018) · Cochrane
no estimate extractedNRNo studies
Resistance testing vs no resistance testing
New opportunistic infection ‐ not reported · HIV‐positive people
Antiretroviral resistance testing in HIV‐positive people (2018) · Cochrane
no estimate extractedNRNo studies
Smectite vs control
Death · acute infectious diarrhoea in children
Smectite for acute infectious diarrhoea in children (2018) · Cochrane
no estimate extractedNRNo studies
Smectite vs control
Serious adverse events · acute infectious diarrhoea in children
Smectite for acute infectious diarrhoea in children (2018) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Clinical malaria (incidence) · people living in malaria‐endemic areas
Larvivorous fish for preventing malaria transmission (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Entomological inoculation rate · people living in malaria‐endemic areas
Larvivorous fish for preventing malaria transmission (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Density of adult malaria vectors · people living in malaria‐endemic areas
Larvivorous fish for preventing malaria transmission (2017) · Cochrane
no estimate extractedNRNo studies
Health promotion activities vs no intervention
Long‐term tuberculosis prevalence · all age groups
Interventions to increase tuberculosis case detection at primary healthcare or community‐level services (2017) · Cochrane
no estimate extractedNRNo studies
Health promotion activities vs no intervention
Treatment success · all age groups
Interventions to increase tuberculosis case detection at primary healthcare or community‐level services (2017) · Cochrane
no estimate extractedNRNo studies
Health promotion activities vs no intervention
Tuberculosis mortality · all age groups
Interventions to increase tuberculosis case detection at primary healthcare or community‐level services (2017) · Cochrane
no estimate extractedNRNo studies