Cochrane · systematic review · CD013694
Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms
Shapiro, AE, Ross, JM, Yao, M, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 2 · 33.3%Low 1 · 16.7%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Xpert MTB/RIF as a screening test for pulmonary tuberculosis in people living with HIV and non‐hospitalized people in high‐risk groups
Population: people living with HIV and non‐hospitalized people in high‐risk groups
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Index test, population | no estimate extracted | NR | No studies |
Xpert MTB/RIF, people living with HIV | no estimate extracted | 12 studies · 602 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Xpert Ultra, people living with HIV | no estimate extracted | 1 study · 68 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Xpert MTB/RIF, non‐hospitalized people in high‐risk groups | no estimate extracted | 5 studies · 337 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Xpert MTB/RIF for detecting rifampicin resistance for high‐risk groups
Population: people in high‐risk groups
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Index test | no estimate extracted | NR | No studies |
Xpert MTB/RIF | no estimate extracted | 2 studies · 20 participants | Very low Downgraded: imprecision, inconsistency, indirectness |