Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
Multistrand StSt versus other materials (conventional StSt, superelastic NiTi, thermoelastic NiTi); alignment rate not pooled due to clinical heterogeneity (Cobb 1998; Evans 1998; Quintao 2005; West 1995); results…
4 studies · 281 participants
Very low
Child microbiological presence (mutans streptococci acquisition) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review
Early childhood caries (ECC) · Preschool children ≤6 years, Asia and Europe
In Asia and Europe, 25(OH)D 50–75 nmol/l (vs ≥75) was associated with higher odds of ECC (OR 1.32; ungraded).
1 finding from 1 review
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) led to lower wits appraisal compared with reverse Twin Block with lip pads and rapid maxillary expander (RME); GRADE not reported.
1 finding from 1 review
Dental caries prevalence · Brazilian children/adolescents (BMI classified by WHO 2007 percentile)
The evidence is very uncertain about the effect of overweight/obesity on caries odds (WHO 2007 percentile; very low certainty).
1 finding from 1 review
Moderate gingival inflammation / gingival health · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…
Gingival inflammation is common among persons with disabilities in Saudi Arabia (moderate-to-severe up to about 60%), reported narratively without a pooled comparative estimate (ungraded).
1 finding from 1 review
Intervention not reported
Fluoride ion release
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask (RME) or modified facemask showed no clear difference in ANB compared with surgically-anchored appliance (miniscrews or miniplates) (low certainty).
1 finding from 1 review
Enamel demineralization (QLF ΔF) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Flash-free brackets showed no clinical WSL reduction, with certainty not graded.
1 finding from 1 review
Intervention not reported
Spontaneous space closure
The intervention led to higher spontaneous space closure; GRADE not reported.
1 finding from 1 review
OR 8.0
1 study
GRADE not reported
Plaque index (PI) / oral hygiene · Children and/or adolescents (<18 years) without background systemic disease
Probiotics may make little to no difference to the bacterial plaque index versus control (MD 0.21, 95%CI -0.55 to 0.96; very low certainty).
1 finding from 1 review
Participant satisfaction or quality of life · People with temporomandibular disorders (TMD)
Occlusal splint led to lower participant satisfaction or quality of life compared with another occlusal splint with a different mechanism of action; GRADE not reported.
1 finding from 1 review
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
Pooling two trials, SDF and nano-silver fluoride showed no significant difference in tooth-level caries arrestment (OR 1.47; ungraded subgroup).
1 finding from 1 review
Sensitivity for dental caries diagnosis · Children and adults with primary or permanent dentition
Sensitivity ranged from 48% to 98.3% across 13 studies; no meta-analysis or GRADE rating was reported.
1 finding from 1 review
d1-4 efs · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs2228570) over-dominant model: AA+GG vs AG was not significantly associated with dental caries (OR 1.04); ungraded.
1 finding from 1 review
Intervention not reported
Dental caries (early childhood caries)
1 finding from 1 review
AOR 3.7
1 study
GRADE not reported
White spot lesion rate and volume · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Clearfil Protect Bond showed no WSL-rate difference versus conventional adhesive, with certainty not graded.
1 finding from 1 review
There was no significant difference among the WSL rates of the Clearfil, Opal Seal, and Transbond XT adhesives (p > 0.05).
1 study · 15 participants
GRADE not reported