Question · asked by 1 review
Serum 25(OH)D 50–75 nmol/l vs Serum 25(OH)D ≥ 75 nmol/l: Early childhood caries (ECC)
- Population
- Preschool children ≤6 years, Asia and Europe
- Intervention
- Serum 25(OH)D 50–75 nmol/l
- Comparison
- Serum 25(OH)D ≥ 75 nmol/l
- Outcome
- Early childhood caries (ECC)
In Asia and Europe, 25(OH)D 50–75 nmol/l (vs ≥75) was associated with higher odds of ECC (OR 1.32; ungraded).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Serum 25(OH)D 50–75 nmol/l vs Serum 25(OH)D ≥ 75 nmol/l Early childhood caries (ECC) · Preschool children ≤6 years, Asia and Europe · Asia and Europe In Asia and Europe, 25(OH)D 50–75 nmol/l (vs ≥75) was associated with higher odds of ECC (OR 1.32; ungraded). The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis. (2024) All outcomes | OR 1.32 [1.17, 1.50] | 3 studies · 4996 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis. 2024 All outcomes | December 2021 to February 2022 | 12 | Not applicable |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Serum 25(OH)D 50–75 nmol/l vs Serum 25(OH)D ≥ 75 nmol/l · Children aged 6 years or younger (preschool children) · 1 review
- Serum 25(OH)D 50–75 nmol/l vs Serum 25(OH)D ≥ 75 nmol/l · Preschool children ≤6 years, North America · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.