Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether extraction of lower deciduous canines changes amount of crowding (lower incisor crowding, change) at 1-2 years compared with no active treatment (control) (very low certainty).
1 finding from 1 review
Dental service utilisation within the past year · Healthy Emirati preschool children in the United Arab Emirates
Utilization of dental services among healthy Emirati preschoolers was very low, with most children never having visited a dentist and very low care indices (narrative synthesis; not GRADE-rated).
1 finding from 1 review
Kowash et al. reported very low utilization of dental services among healthy Emirati preschoolers: two-thirds never visited a dentist, with a very low care/restorative index of 6.4% in Al Ain, and a care index of 3.8%…
2 studies
GRADE not reported
Oral health status (caries, DMFT, calculus, erosion, malocclusion, treatment indices) · Children with Down syndrome in Dubai
One study found children with Down syndrome had similar caries prevalence but higher DMFT, calculus, erosion and malocclusion than controls, with better restorative-care access (narrative synthesis; not GRADE-rated).
1 finding from 1 review
Ghaith et al. (Dubai) reported dental decay in 57.6% of children with Down syndrome (same as controls) but a higher mean DMFT (2.73 vs 1.65) and calculus index (0.25 vs 0.07), higher erosion prevalence/severity, and…
1 study
GRADE not reported
DMFT/DMFS index (dental caries experience) · Adults (general and hospital populations assessed in case-control studies)
No statistically significant difference in DMFT index between SSc patients and controls (SMD -0.03, CI includes 0); certainty ungraded.
1 finding from 1 review
COE with light-based detection (e.g. ViziLite Plus, Microlux/DL, VELscope, Identafi 3000) vs Conventional oral examination (COE) alone
Outcome not reported · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…
The review found no eligible studies for this question.
1 finding from 1 review
Stability of crossbite correction (relapse of molar expansion) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
Dental caries prevalence · School children aged 5-7 years in Dubai schools
Dental caries prevalence was 60.3% in children aged 5-7 years.
1 finding from 1 review
Dental erosion prevalence · Children with Down syndrome in Dubai
Dental erosion prevalence was 34% in children with Down syndrome versus 15.3% in controls.
1 finding from 1 review
Prevalence 34
1 study
GRADE not reported
Dental caries in children · Children in cross-sectional studies from Asia
Maternal smoking during pregnancy was associated with higher odds of childhood caries in the Asia subgroup.
1 finding from 1 review
OR 1.84 [1.39, 2.45]
2 studies
GRADE not reported
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Concomitant (concurrent) chemoradiotherapy led to lower disease-free survival, concurrent chemoradiotherapy vs radiotherapy… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
1 finding from 1 review
HR 0.74 [0.67, 0.80]
13 studies
GRADE not reported
Iron deficiency (as defined by trialists) · Preschool children (<6 years)
In a sensitivity analysis excluding one outlier study, ECC remained associated with higher odds of iron deficiency (OR 2.76, 95% CI 2.42 to 3.13); ungraded.
2 findings from 1 review
Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of IL-6 (pg/mL) compared with no treatment (no periodontal treatment); GRADE not reported.
3 findings from 1 review
Intervention not reported
Dental caries prevalence · General population (children and adults) in East Africa
Caries prevalence in primary dentition was 39.5% (95% CI 26.9 to 52.1); certainty not graded.
1 finding from 1 review
Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
Fixed tooth-bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).
1 finding from 1 review
Fracture of restorations · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6 to 12 years)
Direct composite resin restoration showed no clear difference in fracture of restorations compared with amalgam restoration (low certainty).
1 finding from 1 review
Full-mouth bleeding score (FMBS) · Adolescents/teenagers undergoing orthodontic treatment
A single study reported a lower full-mouth bleeding score with aligners versus fixed appliances in adolescents at 12 months (MD -20.44, 95% CI -22.98 to -17.90; ungraded).
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
The additional use of a sealant probably reduces the initiation of white spot lesions during fixed orthodontic treatment compared with no sealant (RR 0.70), but the certainty of evidence is very low.
1 finding from 1 review
Periodontal disease (periodontitis) coincidence · Patients with ulcerative colitis (UC) and controls without IBD; adults, both sexes
Patients with ulcerative colitis have about 3-fold higher odds of periodontal disease than controls (pooled OR 3.25, 95% CI 2.23-4.74; 5 studies; ungraded).
1 finding from 1 review
Iron deficiency anaemia · Preschool children (<6 years)
Children with early childhood caries were more likely to have iron-deficiency anemia than caries-free children (OR 2.74, 95% CI 2.41 to 3.11); ungraded.
1 finding from 1 review