Findings

What do systematic reviews say?

3,241 questions · 3,336 findings · 1,340 reviews

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No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Risk‐reducing salpingo‐oophorectomy (RRSO) vs no RRSO

Quality of life (ovarian cancer risk perception): BRCA1 or BRCA2

1 finding from 1 review

Risk‐reducing bilateral salpingo‐oophorectomy in women with BRCA1 or BRCA2 mutations 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Very low

Intervention not reported

Quality of life Investigator global assessment Scale from 1 to 7 · patients with essential tremor

1 finding from 1 review

Alprazolam for essential tremor 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Goal setting with or without strategies to enhance goal pursuit vs no goal setting

Health‐related quality of life or self‐reported emotional status · adults with acquired disability participating in rehabilitation

1 finding from 1 review

Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 446 participants
Very low

Goal setting with or without strategies to enhance goal pursuit vs usual care

Health‐related quality of life or self‐reported emotional status · adults with acquired disability participating in rehabilitation

1 finding from 1 review

Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 441 participants
Low

Physical health monitoring vs No monitoring

Quality of life: Loss of activities of Daily Living (ADL) skills · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

PHYSICAL HEALTH ADVICE vs usual care

Quality of life Lehman Quality of Life Scale. Scale from: 1 to 7 · people with severe mental disorders

1 finding from 1 review

General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low

DANCE THERAPY vs usual care

Quality of Life Manchester Short Assessment (MANSA) · patients with schizophrenia

1 finding from 1 review

Dance therapy for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Moderate

Summary of findings: amikacin liposome inhalation suspension (ALIS) vs tobramycin

QoL · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 294 participants
Moderate

Summary of findings: oral antioxidant combination vs control

Quality of life: Quality of Well Being score change from baseline · children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antioxidant supplementation for lung disease in cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: oral antioxidant combination vs control

Quality of life: Quality of Well Being score change from baseline · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antioxidant supplementation for lung disease in cystic fibrosis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

QoL · patients with schizophrenia

1 finding from 1 review

Cognitive behavioural therapy plus standard care versus standard care plus other psychosocial treatments for people… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Very low

Multifocal vs monofocal intraocular lenses after cataract extraction

Participant‐reported outcomes: quality of life or visual function · people with cataract

1 finding from 1 review

Multifocal versus monofocal intraocular lenses after cataract extraction 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 435 participants
Very low

Leg Club vs nurse home visits

Quality of life Spitzer's quality of life index. Scale from 0‐10. · people with venous leg ulcers

1 finding from 1 review

Interventions for helping people adhere to compression treatments for venous leg ulceration 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Low

Surgery vs corticosteroid injection

Health‐related quality of life ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Surgical versus non‐surgical treatment for carpal tunnel syndrome 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SPLINT vs No active treatment (control)

Health‐related quality of life ‐ Long‐term improvement: > 3 months · carpal tunnel syndrome

1 finding from 1 review

Splinting for carpal tunnel syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen

1 finding from 1 review

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Quality of life ‐ after 3 months Number of participants: 61(1 RCT)

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Quality of life (< 1 month post intervention) ‐ social functioning · adult patients with substance dependence

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
48.36 [41.8, 54.92]
1 study · 155 participants
Very low

Exercise vs no exercise

Quality of Life Scale from: ‐1 to 1 with 1 indicating best outcome · Adults with haematological malignancies

Physical exercise showed no clear difference in quality of Life Scale from: ‐1 to 1 with 1 indicating best outcome compared with no physical exercise (low certainty).

1 finding from 1 review

Aerobic physical exercise for adult patients with haematological malignancies 2019 · Cochrane Headline outcomes only
SMD 0.11
8 studies · 1259 participants
Low

Donepezil 10 mg/day vs placebo

Quality of life of participants (change from baseline at 26 weeks) · people with Alzheimer's disease

1 finding from 1 review

Donepezil for dementia due to Alzheimer's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 815 participants
Moderate