Cochrane · systematic review · CD010003

Splinting for carpal tunnel syndrome

Karjalainen, TV, Lusa, V, Page, MJ, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Neuromuscular2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

SPLINT compared to NO ACTIVE TREATMENT for carpal tunnel syndrome

Population: carpal tunnel syndrome
7 questions
OutcomeEffectEvidenceStatus / GRADE
CTS symptoms (Boston CTS questionnaire) ‐ short‐term improvement: < 3 monthsScale: 1 to 5, higher is worse
SPLINT vs NO ACTIVE TREATMENT
no estimate extracted6 studies · 306 participantsLow
Downgraded: risk of bias, inconsistency
CTS symptoms (Boston CTS questionnaire) ‐ long‐term improvement: > 3 monthsScale: 1 to 5, higher is worse
SPLINT vs NO ACTIVE TREATMENT
no estimate extracted2 studies · 144 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Function (Boston CTS questionnaire) ‐ long‐term improvement: > 3 monthsScale: 1 to 5, higher is worse
SPLINT vs NO ACTIVE TREATMENT
no estimate extracted1 study · 34 participantsLow
Downgraded: risk of bias, imprecision
Overall improvement (improved/not improved or worsened) ‐ short‐term improvement: < 3 months
SPLINT vs NO ACTIVE TREATMENT
RR 3.86 [2.29, 6.51]1 study · 80 participantsLow
Downgraded: risk of bias, imprecision
Health‐related quality of life ‐ long‐term improvement: > 3 months
SPLINT vs NO ACTIVE TREATMENT
no estimate extracted0 studies · 0 participantsUngraded
Adverse effects
SPLINT vs NO ACTIVE TREATMENT
RR 15 [0.89, 254.13]1 study · 80 participantsLow
Downgraded: risk of bias, imprecision
Referral for surgery
SPLINT vs NO ACTIVE TREATMENT
RR 0.47 [0.14, 1.58]3 studies · 243 participantsVery low
Downgraded: risk of bias, imprecision