Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

81 questions · 81 findings · 45 reviews

No studies found 17 · 21%GRADE not reported 4 · 4.9%Very low 44 · 54.3%Low 10 · 12.3%Moderate 4 · 4.9%High 2 · 2.5%

Increased vs stable doses of inhaled corticosteroids

Non‐serious adverse events 43 weeks · adults and children with chronic asthma

It is very uncertain whether increased changes non‐serious adverse events 43 weeks compared with stable doses of inhaled corticosteroids (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

Adverse events considered non‐serious · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious compared with placebo or no intervention (very low certainty).

1 finding from 1 review

TACE followed by 3‐DCRT vs chemoembolisation

Non‐serious adverse events: leukopenia · primary hepatocellular carcinoma

It is very uncertain whether TACE followed by 3‐DCRT changes non‐serious adverse events: leukopenia compared with TACE (very low certainty).

1 finding from 1 review

Lactulose vs lactitol

Non‐serious adverse events (secondary outcome) · prevention and treatment of hepatic encephalopathy in people with cirrhosis

It is very uncertain whether lactulose changes non‐serious adverse events (secondary outcome) compared with lactitol (very low certainty).

1 finding from 1 review

Non‐absorbable disaccharides vs placebo or no intervention

Non‐serious adverse events (secondary outcome) · prevention and treatment of hepatic encephalopathy in people with cirrhosis

It is very uncertain whether non‐absorbable disaccharides changes non‐serious adverse events (secondary outcome) compared with placebo/no intervention (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

Non‐serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes non‐serious adverse events assessed using ICH‐GCP compared with lactulose (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs probiotic

Non‐serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

The review found no eligible studies for this question.

1 finding from 1 review