Cochrane · systematic review · CD006499
Botulinum toxin for the treatment of strabismus
Bort-Martí, AR, Rowe, FJ, Ruiz Sifre, L, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 1 · 16.7%Low 3 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsBotulinum toxin versus surgery
Population: adults and children with strabismus
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Improved or corrected strabismusa at 6 or 12 months Botulinum toxin vs surgery | RR 0.72 [0.53, 0.99] | 4 studies · 242 participants | Low Downgraded: risk of bias, imprecision |
Serious adverse events at 6 or 12 months Botulinum toxin vs surgery | no estimate extracted | NR | No studies |
Proportion of participants requiring additional surgery(ies) at 6 or 12 months Botulinum toxin vs surgery | RR 3.05 [1.34, 6.91] | 1 study · 101 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of participants who achieved binocular single vision at 6 or 12 months Botulinum toxin vs surgery | RR 0.88 [0.63, 1.23] | 2 studies · 102 participants | Low Downgraded: risk of bias, imprecision |
Quality of life, as measured by validated instruments Botulinum toxin vs surgery | no estimate extracted | NR | No studies |
Non‐serious adverse events at 6 or 12 months Botulinum toxin vs surgery | no estimate extracted | 3 studies · 212 participants | Low |