Cochrane · systematic review · MR000050
Control interventions in randomised trials among people with mental health disorders
Faltinsen, E, Todorovac, A, Staxen Bruun, L, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
MethodologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
7
No studies
3
Included studies
NR
No studies 3 · 30%Ungraded 0 · 0%Very low 4 · 40%Low 3 · 30%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings
Population: patients with mental health disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Wait‐list compared with no‐treatment | no estimate extracted | NR | No studies |
Summary of findings
Population: patients with mental health disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Usual care compared with wait‐list/no‐treatment (Variety of continuous outcome) (Post‐treatment) | no estimate extracted | 5 studies · 523 participants | Very low |
Serious adverse events for all placebos | no estimate extracted | NR | No studies |
Non‐serious adverse events for all placebos | no estimate extracted | NR | No studies |
Summary of findings
Population: patients with mental health disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All placebos compared with wait‐list or no‐treatment (Variety of continuous outcome) (Post‐treatment) | no estimate extracted | 65 studies · 2446 participants | Low |
Psychological placebos compared with wait‐list or no‐treatment (Variety of continuous outcome) (Post‐treatment) | no estimate extracted | 38 studies · 1263 participants | Low |
Pharmacological placebos compared with wait‐list or no‐treatment (Variety of continuous outcome) (Post‐treatment) | no estimate extracted | 9 studies · 279 participants | Very low |
Physical placebos compared with wait‐list or no‐treatment (Variety of continuous outcome) (Post‐treatment) | no estimate extracted | 17 studies · 896 participants | Low |
Serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) | no estimate extracted | 11 studies · 517 participants | Very low |
Non‐serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) | RD 0.03 | 14 studies · 590 participants | Very low |