What do systematic reviews say?

Interferon vs no intervention

It is very uncertain whether interferon changes health‐related quality of life (1 week) compared with no intervention (very low certainty).

• Pharmacological interventions for acute hepatitis B infection 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Lamivudine vs no intervention

The review found no eligible studies for this question.

• Pharmacological interventions for acute hepatitis B infection 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Other types of high tibial osteotomy (aHTO) vs closing wedge high tibial osteotomy (CW‐HTO)

The review found no eligible studies for this question.

• Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Uncemented fixation with and without hydroxyapatite vs cemented fixation

• Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non‐traumatic… 2012 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 101 participants
  Very low

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator 2019 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 433 participants
  Very low

Absorbable tacks vs absorbable sutures

• Mesh fixation techniques in primary ventral or incisional hernia repair 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Very low

Probiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

• Probiotics for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 222 participants
  Low

Probiotics vs placebo

• Probiotics for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Low

Interventions targeting patients vs usual care or interventions of the same type

The review found no eligible studies for this question.

• Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
  no estimate extracted
  116 participants
  Very low

Interventions targeting healthcare professionals vs usual care or interventions of the same type

• Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
  no estimate extracted
  359 participants
  Low
• Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Interventions targeting healthcare professionals and patients vs usual care or interventions of the same type

• Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
  no estimate extracted
  75 participants
  Very low
• Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Wound drainage for lower limb arterial surgery 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Suprasorb CNP system vs the ABThera system

The review found no eligible studies for this question.

• Negative pressure wound therapy for managing the open abdomen in non‐trauma patients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NPWT vs the Bogota bag

The review found no eligible studies for this question.

• Negative pressure wound therapy for managing the open abdomen in non‐trauma patients 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Autologous blood or PRP vs placebo at 3 months' follow‐up

• Autologous blood and platelet‐rich plasma injection therapy for lateral elbow pain 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

mHealth education intervention vs usual care

• mHealth education interventions in heart failure 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 942 participants
  Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 219 participants
  Very low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 164 participants
  Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 259 participants
  Very low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 200 participants
  Very low