Cochrane · systematic review · CD011563

Mesh fixation techniques in primary ventral or incisional hernia repair

Mathes, T, Prediger, B, Walgenbach, M, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
56
current version
GRADE rated
47
No studies
9
Included studies
NR
No studies 9 · 16.1%Ungraded 0 · 0%Very low 28 · 50%Low 19 · 33.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Absorbable tacks compared to nonabsorbable tacks in primary ventral or incisional hernia repair

Population: People needing incisional hernia repair
4 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (1 year to 31 (median) months)
Absorbable tacks vs nonabsorbable tacks
RR 0.74 [0.17, 3.22]2 studies · 101 participantsVery low
Downgraded: risk of bias, imprecision
Early postoperative pain (VAS 0 ‐ 10, 1 day)
Absorbable tacks vs nonabsorbable tacks
no estimate extracted1 study · 51 participantsVery low
Downgraded: risk of bias, imprecision
Early postoperative pain (VAS 0 ‐ 100, 2 days)
Absorbable tacks vs nonabsorbable tacks
no estimate extracted1 study · 50 participantsLow
Downgraded: risk of bias, imprecision
Early postoperative pain (VAS 0 ‐ 10, 2 weeks)
Absorbable tacks vs nonabsorbable tacks
no estimate extractedNRNo studies

Nonabsorbable tacks compared to nonabsorbable sutures in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
4 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (6 months)
Nonabsorbable tacks vs nonabsorbable sutures
RR 1 [0.07, 14.79]1 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Early postoperative pain (VAS 0 ‐ 10, 1 week)
Nonabsorbable tacks vs nonabsorbable sutures
no estimate extracted1 study · 53 participantsVery low
Downgraded: risk of bias, imprecision
Chronic pain (VAS 0 ‐ 10, 6 to 12 months)
Nonabsorbable tacks vs nonabsorbable sutures
no estimate extracted2 studies · 89 participantsVery low
Downgraded: risk of bias, inconsistency
Health‐related quality of life
Nonabsorbable tacks vs nonabsorbable sutures
no estimate extractedNRNo studies

Absorbable tacks compared to absorbable sutures in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (1 year)
Absorbable tacks vs absorbable sutures
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Early postoperative pain (VAS 0 ‐ 10, sum 0 to 3 days)
Absorbable tacks vs absorbable sutures
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Chronic pain (VAS 0 ‐ 10, 6 months)
Absorbable tacks vs absorbable sutures
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Health‐related quality of life (6 months)
Absorbable tacks vs absorbable sutures
no estimate extracted1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision
Severe postoperative complications
Absorbable tacks vs absorbable sutures
RR 1.43 [0.4, 5.04]1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision

Nonabsorbable tacks plus nonabsorbable sutures compared to nonabsorbable sutures in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (2 years)
Nonabsorbable tacks plus nonabsorbable sutures vs nonabsorbable sutures
RR 4.82 [0.24, 98.03]1 study · 106 participantsVery low
Downgraded: risk of bias, imprecision
Early postoperative pain (VAS 0 ‐ 10, 1 day)
Nonabsorbable tacks plus nonabsorbable sutures vs nonabsorbable sutures
no estimate extracted1 study · 92 participantsVery low
Downgraded: risk of bias, imprecision
Chronic pain (VAS 0 ‐ 10, 3 months)
Nonabsorbable tacks plus nonabsorbable sutures vs nonabsorbable sutures
no estimate extracted1 study · 92 participantsLow
Downgraded: risk of bias, imprecision
Seroma (7 days)
Nonabsorbable tacks plus nonabsorbable sutures vs nonabsorbable sutures
RR 0.64 [0.25, 1.68]1 study · 106 participantsVery low
Downgraded: risk of bias, imprecision
Mesh infection (postoperative not specified)
Nonabsorbable tacks plus nonabsorbable sutures vs nonabsorbable sutures
no estimate extracted1 study · 106 participantsVery low
Downgraded: risk of bias, imprecision

Absorbable tacks plus absorbable sutures compared to nonabsorbable tacks plus nonabsorbable sutures in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
6 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (2 years)
Absorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 77 participantsVery low
Downgraded: risk of bias, imprecision
Early postoperative pain
Absorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extractedNRNo studies
Chronic pain (VAS 0 ‐ 10, 3 months)
Absorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision
Chronic pain (VAS 0 ‐ 10, 6 months)
Absorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 90 participantsLow
Downgraded: risk of bias, imprecision
Health‐related quality of life
Absorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extractedNRNo studies
Seroma (1 week)
Absorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
RR 0.71 [0.24, 2.08]1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision

Nonabsorbable tacks compared to nonabsorbable tacks plus nonabsorbable sutures in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
9 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (3 months)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted2 studies · 185 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Recurrence (2 years)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
RR 0.33 [0.04, 2.82]1 study · 63 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Early postoperative pain (VAS 0 ‐ 10, at rest, 4 hours)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 69 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Early postoperative pain (VAS 0 ‐ 10, coughing, 4 hours)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 69 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Chronic pain (VAS 0 ‐ 10, at rest, 3 months)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 59 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Chronic pain (VAS 0 ‐ 10, coughing, 3 months)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 59 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Chronic pain (VAS 0 ‐ 100, 3 month)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 116 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Health‐related quality of life
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extractedNRNo studies
Seroma (3 month)
Nonabsorbable tacks vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extractedNRNo studies

Nonabsorbable tacks plus absorbable sutures compared to nonabsorbable tacks only in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
6 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only
RR 1.07 [0.07, 16.72]1 study · 116 participantsVery low
Downgraded: risk of bias, imprecision
Early postoperative pain
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only
no estimate extractedNRNo studies
Chronic pain (VAS 0 ‐ 100, 3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only
no estimate extracted1 study · 116 participantsVery low
Downgraded: risk of bias, imprecision
Health‐related quality of life
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only
no estimate extractedNRNo studies
Seroma (3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only
RR 3.21 [0.13, 77.22]1 study · 116 participantsVery low
Downgraded: risk of bias, imprecision
Haematoma (3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks only
RR 1.07 [0.23, 5.09]1 study · 116 participantsVery low
Downgraded: risk of bias, imprecision

Nonabsorbable tacks plus absorbable sutures compared to nonabsorbable tacks plus nonabsorbable sutures in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
RR 3 [0.12, 72.1]1 study · 112 participantsVery low
Downgraded: risk of bias, imprecision
Chronic pain (VAS 0 ‐ 100, 3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extracted1 study · 112 participantsLow
Downgraded: risk of bias, imprecision
Health‐related quality of life
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
no estimate extractedNRNo studies
Seroma (3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
RR 3 [0.12, 72.1]1 study · 112 participantsVery low
Downgraded: risk of bias, imprecision
Haematoma (3 month)
Nonabsorbable tacks plus absorbable sutures vs nonabsorbable tacks plus nonabsorbable sutures
RR 3 [0.32, 27.97]1 study · 112 participantsVery low
Downgraded: risk of bias, imprecision

Nonabsorbable tacks compared to fibrin sealant in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
7 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (1 year)
Nonabsorbable tacks vs fibrin sealant
no estimate extracted2 studies · 88 participantsVery low
Downgraded: imprecision, inconsistency
Early postoperative pain (VAS 0 ‐ 100, 2 days)
Nonabsorbable tacks vs fibrin sealant
no estimate extracted50 participantsLow
Downgraded: imprecision, inconsistency
Pain (up to 1 year)
Nonabsorbable tacks vs fibrin sealant
no estimate extracted1 study · 50 participantsLow
Downgraded: imprecision, inconsistency
Health‐related quality of life (up to 1 year)
Nonabsorbable tacks vs fibrin sealant
no estimate extracted1 study · 50 participantsLow
Downgraded: imprecision, inconsistency
Seroma (30 days)
Nonabsorbable tacks vs fibrin sealant
RR 0.93 [0.54, 1.61]2 studies · 88 participantsLow
Downgraded: imprecision, inconsistency
Haematoma (30 days)
Nonabsorbable tacks vs fibrin sealant
RR 0.75 [0.19, 2.91]1 study · 38 participantsLow
Downgraded: imprecision, inconsistency
Superficial infection (30 days)
Nonabsorbable tacks vs fibrin sealant
RR 0.95 [0.52, 1.74]2 studies · 88 participantsVery low
Downgraded: imprecision, inconsistency

Absorbable tacks compared to fibrin sealant in primary ventral or incisional hernia repair

Population: People with primary ventral or incisional hernia repair
5 questions
OutcomeEffectEvidenceStatus / GRADE
Recurrence (1 year)
Absorbable tacks vs fibrin sealant
RR 3 [0.13, 70.3]1 study · 50 participantsLow
Downgraded: imprecision
Early postoperative pain (VAS 0 ‐ 100, 2 days)
Absorbable tacks vs fibrin sealant
no estimate extracted1 study · 50 participantsLow
Downgraded: imprecision
Pain (up to 1 year)
Absorbable tacks vs fibrin sealant
no estimate extracted1 study · 50 participantsLow
Downgraded: imprecision
Health‐related quality of life (up to 1 year)
Absorbable tacks vs fibrin sealant
no estimate extracted1 study · 50 participantsLow
Downgraded: imprecision
Infection (1 month)
Absorbable tacks vs fibrin sealant
RR 1 [0.07, 15.12]1 study · 50 participantsLow
Downgraded: imprecision