Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,918 questions · 5,537 findings · 1,803 reviews

No studies found 1,309 · 23.6%GRADE not reported 440 · 7.9%Very low 1,560 · 28.2%Low 1,292 · 23.3%Moderate 751 · 13.6%High 185 · 3.3%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Erythromycin vs placebo

Adverse events: minor gastrointestinal symptoms · pityriasis rosea

Erythromycin showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo

Adverse events Assessed as: occurrence of one or more major adverse events requiring withdrawal of treatment · people with nerve damage (< 6 months' duration) in leprosy

Corticosteroids showed no clear difference in adverse events Assessed as: occurrence of one or more major adverse… compared with placebo (moderate certainty).

1 finding from 1 review

Heated humidification + fixed CPAP vs fixed CPAP

Adverse events (machine tolerability outcomes) assessed as number of participants experiencing a blocked nose · adults with a diagnosis of sleep apnoea

Heated humidification + fixed CPAP may leads to lower adverse events (machine tolerability outcomes) assessed as number of… compared with fixed CPAP alone (low certainty).

1 finding from 1 review

Intervention vs no intervention or control intervention (control)

Serious adverse events (number) ‐ pegylated interferon‐alpha plus ribavirin versus pegylated interferon‐alpha · people with acute hepatitis C infection

It is very uncertain whether intervention changes serious adverse events (proportion) ‐ pegylated interferon‐alpha… compared with no intervention or control intervention (control) (very low certainty).

2 findings from 1 review

RISPERIDONE DEPOT vs GENERAL ORAL ANTIPSYCHOTICS

Adverse events: Nervous system disorders (inc. EPS) ‐ long term It is unclear how adverse events were reported · patients with schizophrenia

It is very uncertain whether RISPERIDONE DEPOT changes adverse events: Nervous system disorders (inc. EPS) ‐ long term It… compared with GENERAL ORAL ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Movement therapies vs usual care

Adverse events post‐intervention Number of people reporting an adverse event before completing the intervention · patients with fibromyalgia

It is very uncertain whether movement therapies changes adverse events post‐intervention Number of people reporting an… compared with usual care (very low certainty).

1 finding from 1 review

Psychological therapies vs usual care

Adverse events post‐intervention Number of people reporting an adverse event before completing the intervention · patients with fibromyalgia

Psychological therapies showed no clear difference in adverse events post‐intervention Number of people reporting an… compared with usual care (low certainty).

1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Adverse events: all ‐ other events ‐ not listed above (e.g. dysuria, neck pain, eye discomfort) (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes adverse events: all ‐ other events ‐ not listed above (e.g.… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Thyroxine vs placebo or no treatment

Adverse events including maternal pregnancy complications, foetal complications and adverse effects of thyroxine · subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism

Thyroxine led to lower adverse events including maternal pregnancy complications, foetal… compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Intervention not reported

The proportion of patients who discontinued study drug because of adverse events excluding relapses at two years · Patients with relapsing‐remitting multiple sclerosis

The intervention probably leads to higher the proportion of patients who discontinued study drug because of… (moderate certainty).

1 finding from 1 review