Cochrane · systematic review · CD009921

Automated telephone communication systems for preventive healthcare and management of long‐term conditions

Posadzki, P, Mastellos, N, Ryan, R, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Consumers and CommunicationAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
79
current version
GRADE rated
48
No studies
14
Included studies
NR
No studies 14 · 17.7%Ungraded 17 · 21.5%Very low 2 · 2.5%Low 23 · 29.1%Moderate 20 · 25.3%High 3 · 3.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Preventive healthcare: effects of ATCS on health services uptake (immunisations)

Population: participants at risk of under‐immunisation (children, adolescents and adults)
4 questions
OutcomeEffectEvidenceStatus / GRADE
Behavioural outcome: immunisation rate ATCS Plus, IVR, unidirectional versus no calls, letters, usual care at median
RR 1.25 [1.18, 1.32]5 studies · 10454 participantsModerate
Downgraded: risk of bias, imprecision
Behavioural outcome: immunisation rate Unidirectional ATCS versus usual care at median
RR 1.06 [1.02, 1.11]2 studies · 5725 participantsModerate
Downgraded: risk of bias
Behavioural outcome: immunisation rate Unidirectional ATCS versus no calls or health information at median
RR 2.18 [0.53, 9.02]2 studies · 1743 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Adverse outcome: unintended adverse events attributable to the intervention ATCS+, IVR, unidirectional versus various controls
no estimate extractedNRNo studies

Preventive healthcare: effects of ATCS on physical activity levels

Population: participants at risk of developing long‐term conditions
7 questions
OutcomeEffectEvidenceStatus / GRADE
Behavioural outcome: physical activity Multimodal/complex interventionb versus no calls
no estimate extracted1 study · 181 participantsLow
Downgraded: risk of bias, imprecision
Behavioural outcome: physical activity, 12 months Multimodal/complex interventiond versus usual care
no estimate extracted2 studies · 700 participantsUngraded
Behavioural outcome: physical activity ATCS Plus versus IVR control
no estimate extracted2 studies · 369 participantsLow
Downgraded: risk of bias, imprecision
Behavioural outcome: physical activity IVR versus usual care, control or health education
no estimate extracted3 studies · 216 participantsLow
Downgraded: risk of bias, imprecision
Clinical outcome: metabolic markers, 12 months Multimodal/complex interventiond versus usual care
no estimate extracted1 study · 302 participantsLow
Downgraded: risk of bias, imprecision
Clinical outcome: body weight measures Multimodal/complex interventiond ATCS Plus versus usual care or control
no estimate extracted2 studies · 373 participantsLow
Downgraded: risk of bias, imprecision
Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR versus various controls
no estimate extractedNRNo studies

Preventive healthcare: effects of ATCS on health services uptake (screening)

Population: participants at risk for breast, colorectal or cervical cancer; or osteoporosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Behavioural outcome: breast cancer screening Multimodal/complex intervention versus usual care at 12 months
RR 2.17 [1.55, 3.04]2 studies · 462 participantsHigh
Behavioural outcome: breast cancer screening IVR versus enhanced usual care at median
RR 1.05 [0.99, 1.11]2 studies · 2599 participantsModerate
Downgraded: risk of bias, imprecision
Behavioural outcome: colorectal cancer screening Multimodal/complex intervention versus usual care at median
RR 2.19 [1.88, 2.55]3 studies · 1013 participantsHigh
Behavioural outcome: colorectal cancer screening IVR versus usual care at 6‐month
RR 1.36 [1.25, 1.48]2 studies · 16915 participantsModerate
Downgraded: risk of bias, imprecision
Behavioural outcome: colorectal cancer screening IVR, unidirectional ATCS versus usual care or letter at longer (9‐12 months)
RR 1.01 [0.97, 1.05]2 studies · 21335 participantsModerate
Downgraded: risk of bias, imprecision
Behavioural outcome: cervical cancer screening ATCS Plus versus control (no calls) at 3 month
no estimate extracted1 study · 75532 participantsModerate
Downgraded: risk of bias
Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional versus various controls
no estimate extractedNRNo studies

Preventive healthcare: effects of ATCS on weight management

Population: overweight or obese individuals (both children and adults)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Clinical and behavioural outcome: BMI score in adults Multimodal/complex intervention, ATCS Plus or IVR versus usual care at median
no estimate extracted3 studies · 672 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Clinical and behavioural outcome: body weight in adults, 12 weeks
no estimate extractedNRNo studies
Clinical and behavioural outcome: body weight in adults, at median
no estimate extractedNRNo studies
Clinical and behavioural outcome: blood pressure, blood glucose, cholesterol levels
no estimate extractedNRNo studies
Clinical outcome: BMI z‐score in children at median
no estimate extractedNRModerate
Behavioural outcome: physical activity, dietary habits in children at median
no estimate extractedNRModerate
Downgraded: risk of bias, imprecision, inconsistency
Adverse outcome: unintended adverse events attributable to the intervention IVR versus usual care
no estimate extracted2 studies · 559 participantsUngraded

Preventive healthcare or management of long‐term conditions: effects of ATCS as appointment reminders/reducing non‐attendance rates

Population: patients/healthcare consumers
7 questions
OutcomeEffectEvidenceStatus / GRADE
Health behaviour: attendance rates, 6 weeks ATCS Plus versus nurse‐delivered calls
no estimate extracted1 study · 3610 participantsModerate
Downgraded: risk of bias
Health behaviour: attendance rates, 4 months IVR versus no calls
no estimate extracted1 study · 12092 participantsHigh
Health behaviour: return tuberculin test rate, 3 days Unidirectional ATCS versus no calls
no estimate extracted1 study · 701 participantsLow
Downgraded: risk of bias
Health behaviour: attendance rates, 1 month Unidirectional ATCS versus no calls
no estimate extracted1 study · 517 participantsLow
Downgraded: risk of bias
Health behaviour: attendance rates, 6‐8 weeks Unidirectional ATCS versus no calls
no estimate extracted2 studies · 3304 participantsModerate
Downgraded: risk of bias
Health behaviour: attendance rates, 6 months Unidirectional ATCS versus no calls
no estimate extracted1 study · 2008 participantsLow
Downgraded: risk of bias
Adverse outcome: unintended adverse events attributable to the intervention ATCS Plus, IVR, unidirectional ATCS versus various controls
no estimate extractedNRNo studies

Long‐term management: effects of ATCS on adherence to medication or laboratory tests

Population: patients with various conditions or at risk of low adherence to medication or laboratory tests
9 questions
OutcomeEffectEvidenceStatus / GRADE
Behavioural outcome: adherence to medication Multimodal/complex interventionsb versus usual care or control
no estimate extracted2 studies · 888 participantsUngraded
Behavioural outcome: adherence to medication ATCS Plus versus control or single IVR call
no estimate extracted2 studies · 2340 participantsUngraded
Behavioural outcome: adherence to laboratory tests ATCS Plus or IVR versus no intervention or usual care
no estimate extracted3 studies · 15218 participantsUngraded
Behavioural outcome: adherence to medication or composite outcome (medication adherence and rate of adverse events) ATCS Plus versus usual care
no estimate extracted4 studies · 35816 participantsUngraded
Behavioural outcome: adherence to medication or laboratory tests IVR versus control
no estimate extracted4 studies · 4238362 participantsUngraded
Behavioural outcome: adherence to medication IVR versus usual care
no estimate extracted8 studies · 56140 participantsUngraded
Behavioural outcome: adherence to medication Unidirectional ATCS versus control
no estimate extracted2 studies · 107 participantsUngraded
Clinical outcome: blood pressure Multimodal/complex, ATCS Plus, IVR versus usual care
no estimate extracted3 studies · 22597 participantsUngraded
Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional versus various controls
no estimate extractedNRNo studies

Long‐term management: effects of ATCS on alcohol consumption

Population: participants addicted to alcohol
7 questions
OutcomeEffectEvidenceStatus / GRADE
Behavioural outcomes: number of drinks per drinking day ATCS Plus, IVR versus usual care, (various) controls at median
no estimate extracted3 studies · 459 participantsLow
Downgraded: risk of bias
Behavioural outcomes: drinking days, heavy drinking days, or total number of drinks consumed ATCS Plus, IVR versus (various) controls
no estimate extracted3 studies · 217 participantsLow
Downgraded: risk of bias
Behavioural outcomes: proportion of days abstinent, other alcohol consumption indices, 12 weeks ATCS Plus versus control (packaged CBT)
no estimate extracted1 study · 110 participantsLow
Downgraded: risk of bias
Behavioural outcomes: weekly alcohol consumption, 6 months ATCS Plus versus usual care
no estimate extracted1 study · 338 participantsLow
Downgraded: risk of bias
Behavioural outcomes: AUDIT score, 6 weeks IVR versus control (no intervention)
no estimate extracted1 study · 1423 participantsModerate
Downgraded: risk of bias
Behavioural outcomes: other alcohol consumption indices, 4 weeks IVR versus control (no intervention)
no estimate extracted1 study · 98 participantsLow
Downgraded: risk of bias
Adverse outcome: unintended adverse events attributable to the intervention ATCS Plus, IVR versus various controls
no estimate extractedNRNo studies

Long‐term management: effects of ATCS on severity of cancer symptoms

Population: cancer patients
7 questions
OutcomeEffectEvidenceStatus / GRADE
Clinical outcomes: symptoms (severity or burden) ATCS Plus versus usual care (via ATCS) or control, 4‐12 weeks
no estimate extracted4 studies · 701 participantsUngraded
Clinical outcomes: symptom severity, 10 weeks IVR versus nurse delivered calls
no estimate extracted1 study · 437 participantsLow
Downgraded: risk of bias, imprecision
Clinical outcomes: pain Multimodal/complex interventiong versus usual care
no estimate extracted1 study · 405 participantsModerate
Downgraded: risk of bias, imprecision
Clinical outcomes: depression Multimodal/complex interventiong versus usual care
no estimate extracted1 study · 405 participantsModerate
Downgraded: risk of bias, imprecision
Clinical outcomes:distress, 6 weeks ATCS Plus versus usual care (via IVR)
no estimate extracted1 study · 250 participantsModerate
Downgraded: risk of bias, imprecision
Behavioural outcome: medication adherence ATCS Plus versus usual care
no estimate extracted1 study · 119 participantsLow
Downgraded: risk of bias, imprecision
Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR versus various controls
no estimate extractedNRNo studies

Long‐term management: effects of ATCS in the management of diabetes mellitus

Population: patients with diabetes mellitus
6 questions
OutcomeEffectEvidenceStatus / GRADE
Clinical outcome: glycated haemoglobin or blood glucose ATCS Plus, IVR versus usual care at median
no estimate extracted7 studies · 1216 participantsLow
Downgraded: risk of bias, inconsistency
Behavioural outcome: self‐monitoring of diabetic foot (various scales) ATCS Plus versus usual care at 12 months
no estimate extracted2 studies · 498 participantsModerate
Downgraded: risk of bias, imprecision
Behavioural outcome: self‐monitoring of blood glucose ATCS Plus, IVR versus usual care, 6‐12 months
no estimate extractedNRNo studies
Behavioural outcome: medication adherence or use ATCS Plus versus usual care, 6‐12 months
no estimate extracted2 studies · 370 participantsUngraded
Behavioural outcome: physical activity, diet, weight monitoring ATCS Plus versus usual care, 6‐12 months
no estimate extracted3 studies · 1028 participantsUngraded
Adverse outcome: unintended adverse events attributable to the intervention ATCS Plus, IVR versus usual care
no estimate extractedNRNo studies

Long‐term management: effects of ATCS in patients with heart failure

Population: patients with heart failure
7 questions
OutcomeEffectEvidenceStatus / GRADE
Clinical outcome: cardiac mortality ATCS Plus, IVR versus usual care or usual community care at median
RR 0.6 [0.21, 1.67]2 studies · 215 participantsVery low
Downgraded: risk of bias, imprecision
Clinical outcome: all‐cause mortality ATCS Plus versus usual care or usual community care at median
RR 1 [0.79, 1.28]3 studies · 2165 participantsModerate
Downgraded: risk of bias, imprecision
Clinical outcome: heart failure hospitalisation ATCS Plus, IVR versus usual care or usual community care at median
no estimate extracted4 studies · 2329 participantsUngraded
Clinical outcome: all‐cause hospitalisation ATCS Plus versus usual care or usual community care
no estimate extracted3 studies · 2191 participantsUngraded
Clinical outcome: global health (well‐being) rating (7‐item questionnaire) ATCS Plus versus usual care 12 months
no estimate extracted1 study · 405 participantsModerate
Downgraded: imprecision
Clinical outcome: emergency room and other health service use outcomes ATCS Plus versus usual care or usual community care
no estimate extracted2 studies · 1786 participantsUngraded
Adverse outcome: unintended adverse events attributable to the intervention ATCS Plus, IVR versus usual care
no estimate extracted2 studies · 1791 participantsUngraded

Long‐term management: effects of ATCS in the management of hypertension

Population: patients with hypertension
7 questions
OutcomeEffectEvidenceStatus / GRADE
Clinical outcome: systolic blood pressure (automated sphygmomanometer or electronic pressure monitor) ATCS Plus or IVR versus usual care at median
no estimate extracted3 studies · 65256 participantsModerate
Downgraded: risk of bias, imprecision
Clinical outcome: diastolic blood pressure (automated sphygmomanometer and electronic cuff) ATCS Plus, unidirectional versus usual care at median
no estimate extracted2 studies · 65056 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Clinical outcome: blood pressure control, 26 weeks Multimodal/complex interventionf versus usual care
no estimate extracted1 study · 166 participantsModerate
Downgraded: risk of bias
Clinical outcome: Health statush, depressioni, 6 weeks ATCS Plus versus enhanced usual care (plus information)
no estimate extracted1 study · 200 participantsLow
Downgraded: risk of bias
Behavioural outcome: medication use Multimodal/complexk, ATCS Plus versus usual care or enhanced usual care (plus information)
no estimate extracted2 studies · 483 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Behavioural outcome: physical activity levels, 12 weeks IVR versus enhanced usual care
no estimate extracted1 study · 253 participantsLow
Downgraded: risk of bias
Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional ATCS versus various controls
no estimate extractedNRNo studies

Long‐term management: effects of ATCS on smoking cessation

Population: patients with tobacco dependence
4 questions
OutcomeEffectEvidenceStatus / GRADE
Behavioural outcome: smoking abstinence Multimodal/complex intervention, ATCS Plus, IVR versus (various) controls or usual care at median
RR 1.2 [0.98, 1.46]7 studies · 2915 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Behavioural outcome: medication use Multimodal/complex, ATCS Plus versus control (inactive IVR or self‐help booklet)
no estimate extracted2 studies · 1127 participantsModerate
Downgraded: imprecision
Behavioural outcome: support programme enrolment ATCS Plus versus control (inactive IVR)
no estimate extracted1 study · 521 participantsLow
Downgraded: risk of bias, imprecision
Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR versus various controls
no estimate extractedNRNo studies