Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence-Based Risk Models and…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Zhang et al. 2023 matched by author and year (probable) | NR | 6 | none stated | not extracted yet |
| Machine learning models for predicting recurrence and malignant transformation of oral leukoplakia. Pedroso 2026 · Pedroso Caique Mariano, Claret Anderson Faria, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:41109769 | 2026 | 1 | none stated | not extracted yet |
| Predicting Malignant Transformation in Oral Leukoplakia: A Multilayer Perceptron Approach Incorporating Clinicopathological Features and DNA Content. Pontes 2026 · Pontes Guilherme Iani, Araújo Anna Luíza Damaceno, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:41220072 | 2026 | 1 | 1 | not extracted yet |
| Independent Multicentre Validation of the 'Six-Point' Model for Malignant Transformation Risk in Oral Epithelial Dysplasia. Mahmood 2025 · Mahmood Hanya, Bradburn Mike, et al. · Oral diseases PMID:41450095 | 2026 | 1 | none stated | not extracted yet |
| A novel AI-based score for assessing the prognostic value of intra-epithelial lymphocytes in oral epithelial dysplasia. Shephard 2025 · Shephard Adam J, Mahmood Hanya, et al. · British journal of cancer PMID:39616233 | 2025 | 1 | none stated | not extracted yet |
| Diagnostic Criteria for Oral Epithelial Dysplasia: Predicting Malignant Transformation. Rodrigues 2025 · Rodrigues Amanda Zimmer, Laureano Natalia Koerich, et al. · Head and neck pathology PMID:39918668 | 2025 | 1 | 1 | not extracted yet |
| Binary- and Three-Tiered Oral Epithelial Dysplasia Grading System and Malignant Transformation. Ellonen 2025 · Ellonen Riikka, Kelppe Jetta, et al. · Oral diseases PMID:40231735 | 2025 | 1 | 1 | not extracted yet |
| Risk Assessment of Oral Leukoplakia by Individual Dysplasia Features. Soares 2025 · Soares Andresa Borges, Warnakulasuriya Saman, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:40432218 | 2025 | 1 | none stated | not extracted yet |
| Clinico-Pathological Assessment and Malignant Transformation in Patients with Oral Epithelial Dysplasia - A Follow-up Cohort Study. Yasothkumar 2025 · Yasothkumar Dinesh, Ramani Pratibha, et al. · Head and neck pathology PMID:40758174 | 2025 | 1 | 1 | not extracted yet |
| Architectural and cytological features of epithelial dysplasia associated with transformation risk. Cai 2024 · Cai Xinjia, Zhang Jianyun, et al. · Oral diseases PMID:37983891 | 2024 | 1 | 1 | not extracted yet |
| A fully automated and explainable algorithm for predicting malignant transformation in oral epithelial dysplasia. Shephard 2024 · Shephard Adam J, Bashir Raja Muhammad Saad, et al. · NPJ precision oncology PMID:38942998 | 2024 | 1 | 1 | not extracted yet |
| Oral leukoplakia: A clinicopathological study and malignant transformation. Tovaru 2023 · Tovaru Serban, Costache Mariana, et al. · Oral diseases PMID:34982498 | 2023 | 1 | 1 | not extracted yet |
| Oral leukoplakia classification and staging system with incorporation of differentiated dysplasia. Brouns 2023 · Brouns Elisabeth R, Evren Ilkay, et al. · Oral diseases PMID:35765231 | 2023 | 1 | 1 | not extracted yet |
| Oral epithelial dysplasia grading: Comparing the binary system to the traditional 3-tier system, an actuarial study with malignant transformation as… Sperandio 2023 · Sperandio Marcelo, Warnakulasuriya Saman, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:36177736 | 2023 | 1 | 1 | not extracted yet |
| Histopathological findings of oral epithelial dysplasias and their relation to malignant transformation. Ellonen 2023 · Ellonen Riikka, Suominen Auli, et al. · Cancer treatment and research communications PMID:36481601 | 2023 | 1 | 1 | not extracted yet |
| Deep learning-based pathology image analysis predicts cancer progression risk in patients with oral leukoplakia. Zhang 2023 · Zhang Xinyi, Gleber-Netto Frederico O, et al. · Cancer medicine PMID:36721313 | 2023 | 1 | 1 | not extracted yet |
| Development of a Pathomics-Based Model for the Prediction of Malignant Transformation in Oral Leukoplakia. Cai 2023 · Cai Xinjia, Li Long, et al. · Laboratory investigation; a journal of technical methods and pathology PMID:37164265 | 2023 | 1 | 1 | not extracted yet |
| Assessing Oral Epithelial Dysplasia Risk for Transformation to Cancer: Comparison Between Histologic Grading Systems Versus S100A7… Darling 2023 · Darling Mark Roger, Hwang Jason T K, et al. · Applied immunohistochemistry & molecular morphology : AIMM PMID:37249075 | 2023 | 1 | 1 | not extracted yet |
| A digital score of peri-epithelial lymphocytic activity predicts malignant transformation in oral epithelial dysplasia. Bashir 2023 · Bashir Raja Muhammad Saad, Shephard Adam J, et al. · The Journal of pathology PMID:37294162 | 2023 | 1 | 1 | not extracted yet |
| The role of differentiated dysplasia in the prediction of malignant transformation of oral leukoplakia. Wils 2023 · Wils Leon J, Poell Jos B, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:37749621 | 2023 | 1 | 1 | not extracted yet |
| Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia. Mahmood 2023 · Mahmood Hanya, Shephard Adam, et al. · British journal of cancer PMID:37758836 | 2023 | 1 | 1 | not extracted yet |
| Prediction of malignant transformation and recurrence of oral epithelial dysplasia using architectural and cytological feature specific prognostic… Mahmood 2022 · Mahmood Hanya, Bradburn Mike, et al. · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc PMID:35361889 | 2022 | 1 | 1 | not extracted yet |
| Effect of clinical and histologic features on time to malignancy in 224 cases of oral leukoplakia treated by surgery. Bagan 2022 · Bagan Jose, Martorell Miguel, et al. · Clinical oral investigations PMID:35474554 | 2022 | 1 | 1 | not extracted yet |
| Malignant transformation of oral leukoplakia: a multicentric retrospective study in Brazilian population. Cerqueira 2021 · Cerqueira J-M, Pontes F-S, et al. · Medicina oral, patologia oral y cirugia bucal PMID:33247570 | 2021 | 1 | 1 | not extracted yet |
| Malignant transformation in a cohort of patients with oral epithelial dysplasia. Hankinson 2021 · Hankinson P M, Mohammed-Ali R I, et al. · The British journal of oral & maxillofacial surgery PMID:34303542 | 2021 | 1 | 1 | not extracted yet |
| Oral Leukoplakia and Risk of Progression to Oral Cancer: A Population-Based Cohort Study. Chaturvedi 2020 · Chaturvedi Anil K, Udaltsova Natalia, et al. · Journal of the National Cancer Institute PMID:31860085 | 2020 | 1 | 1 | not extracted yet |
| Malignant transformation of oral leukoplakia: a follow-up study. Jayasooriya 2020 · Jayasooriya Primali Rukmal, Dayaratne Kitmini, et al. · Clinical oral investigations PMID:32436158 | 2020 | 1 | 1 | not extracted yet |
| Malignant transformation rate of oral leukoplakia in an Australian population. Shearston 2019 · Shearston Kate, Fateh Behrooz, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:31172563 | 2019 | 1 | 1 | not extracted yet |
| Predicting malignant progression in clinically high-risk lesions by DNA ploidy analysis and dysplasia grading. Zaini 2018 · Zaini Zuraiza Mohamad, McParland Helen, et al. · Scientific reports PMID:30367100 | 2018 | 1 | 1 | not extracted yet |
| Malignant transformation of oral leukoplakia in a well-defined cohort of 144 patients. Brouns 2014 · Brouns Erea, Baart Ja, et al. · Oral diseases PMID:23521625 | 2014 | 1 | 1 | not extracted yet |
| Malignant transformation of oral epithelial dysplasia: a real-world evaluation of histopathologic grading. Dost 2014 · Dost F, Lê Cao K, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:24388536 | 2014 | 1 | 1 | not extracted yet |
| Malignant transformation of oral leukoplakia: a follow-up study of a hospital-based population of 166 patients with oral leukoplakia from The… Schepman 1998 · Schepman K P, van der Meij E H, et al. · Oral oncology PMID:9813722 | 1998 | 1 | 1 | not extracted yet |
| Bagan 2022 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Bashir 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Bashir 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Brouns 2014 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Brouns 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Cerqueira 2021 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Chaturvedi 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Darling 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Dost 2014 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Ellonen 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Ellonen 2025 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Hankinson 2021 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Jayasooriya 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Mahmood 2022 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Mahmood 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Mahmood 2025 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Pedroso 2026 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Pontes 2026 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |