Primary study · included by 1 review

Oral epithelial dysplasia grading: Comparing the binary system to the traditional 3-tier system, an actuarial study with malignant transformation as outcome.

Sperandio 2023 · Sperandio Marcelo, Warnakulasuriya Saman, Soares Andresa Borges, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2023

Included by

Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence-Based Risk Models and Pathologist-Based Microscopy.

Non-Cochrane · prognostic · 2026 · cited as Sperandio 2023 · Table 1; reference 12

Outcome this study informs	Pooled effect	Evidence	Certainty
Malignant transformation to oral squamous cell carcinoma Pathologist-based H&E microscopy: high-risk dysplasia category (all grading systems combined) vs Low-risk category or no dysplasia · Minimum follow-up 5 to 72 months	OR 3.42 [2.07, 5.68]	22 studies · 7554 participants	GRADE not reported

1 including review in total.