evidencegaps
Primary study · included by 1 review

Assessing Oral Epithelial Dysplasia Risk for Transformation to Cancer: Comparison Between Histologic Grading Systems Versus S100A7 Immunohistochemical Signature-based Grading.

Darling 2023 · Darling Mark Roger, Hwang Jason T K, Dickson Benjamin J, et al. · Applied immunohistochemistry & molecular morphology : AIMM · 2023

Included by

Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence-Based Risk Models and Pathologist-Based Microscopy.
Non-Cochrane · prognostic · 2026 · cited as Darling 2023 · Table 1; reference 46
Outcome this study informsPooled effectEvidenceCertainty
Malignant transformation to oral squamous cell carcinoma
Pathologist-based H&E microscopy: high-risk dysplasia category (all grading systems combined) vs Low-risk category or no dysplasia · Minimum follow-up 5 to 72 months
OR 3.42 [2.07, 5.68]22 studies · 7554 participantsGRADE not reported

1 including review in total.