Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Cyclooxygenase-2 selective inhibitors increase the risk of alveolar osteitis: A systematic review and meta-analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: A single-center, randomized, double-blind, placebo- and… Malmstrom 2002 · Malmstrom Kerstin, Fricke James R., et al. · Clinical Therapeutics DOI:10.1016/s0149-2918(02)80059-5 | 2002 | 2 | 3 | not extracted yet |
| A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and… Malmstrom 2002 · Malmstrom Kerstin, Fricke James R, et al. · Clinical therapeutics PMID:12462285 | 2002 | 2 | none stated | not extracted yet |
| Evaluation of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: A Pilot, Dose-Ranging, Randomized… Kellstein 2020 · Kellstein David, Leyva Rina · Drugs in R&D DOI:10.1007/s40268-020-00310-7 | 2020 | 1 | 1 | not extracted yet |
| Evaluation of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: A Pilot, Dose-Ranging, Randomized… Kellstein 2020 · Kellstein David, Leyva Rina · Drugs in R&D PMID:32506309 | 2020 | 1 | none stated | not extracted yet |
| Longer analgesic effect with naproxen sodium than ibuprofen in post-surgical dental pain: a randomized, double-blind, placebo-controlled,… Cooper 2019 · Cooper Stephen A., Desjardins Paul, et al. · Current Medical Research and Opinion DOI:10.1080/03007995.2019.1655257 | 2019 | 1 | 1 | not extracted yet |
| Longer analgesic effect with naproxen sodium than ibuprofen in post-surgical dental pain: a randomized, double-blind, placebo-controlled,… Cooper 2019 · Cooper Stephen A, Desjardins Paul, et al. · Current medical research and opinion PMID:31402718 | 2019 | 1 | none stated | not extracted yet |
| Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar… Weiser 2018 · Weiser T, Richter E, et al. · European journal of pain (London, England) PMID:28805281 | 2018 | 1 | none stated | not extracted yet |
| Efficacy and safety of a fixed‐dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar… Weiser 2018 · Weiser T., Richter E., et al. · European Journal of Pain DOI:10.1002/ejp.1068 | 2017 | 1 | 1 | not extracted yet |
| Assessment of the Efficacy and Safety Profiles of Aspirin and Acetaminophen With Codeine: Results From 2 Randomized, Controlled Trials in… Gatoulis 2012 · Gatoulis Sergio C., Voelker Michael, et al. · Clinical Therapeutics DOI:10.1016/j.clinthera.2011.11.018 | 2012 | 1 | 1 | not extracted yet |
| A Phase 2 Study Evaluating the Efficacy and Safety of a Novel, Proprietary, Nano-Formulated, Lower Dose Oral Diclofenac Manvelian 2012 · Manvelian Garen, Daniels Stephen, et al. · Pain Medicine DOI:10.1111/j.1526-4637.2012.01479.x | 2012 | 1 | 2 | not extracted yet |
| Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in… Gatoulis 2012 · Gatoulis Sergio C, Voelker Michael, et al. · Clinical therapeutics PMID:22169050 | 2012 | 1 | none stated | not extracted yet |
| A phase 2 study evaluating the efficacy and safety of a novel, proprietary, nano-formulated, lower dose oral diclofenac. Manvelian 2012 · Manvelian Garen, Daniels Stephen, et al. · Pain medicine (Malden, Mass.) PMID:23043637 | 2012 | 1 | none stated | not extracted yet |
| Evaluation of the Dose Range of Etoricoxib in an Acute Pain Setting Using the Postoperative Dental Pain Model Daniels 2011 · Daniels Stephen E., Bandy Donald P., et al. · The Clinical Journal of Pain DOI:10.1097/ajp.0b013e3181ed0639 | 2011 | 1 | 2 | not extracted yet |
| A Double-Blind Placebo-Controlled Comparison of a Novel Formulation of Intravenous Diclofenac and Ketorolac for Postoperative Third Molar Extraction… Christensen 2011 · Christensen Kyle, Daniels Stephen, et al. · Anesthesia Progress DOI:10.2344/0003-3006-58.2.73 | 2011 | 1 | 1 | not extracted yet |
| Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model. Daniels 2011 · Daniels Stephen E, Bandy Donald P, et al. · The Clinical journal of pain PMID:21188849 | 2011 | 1 | none stated | not extracted yet |
| The cyclooxygenase-2 inhibitor celecoxib and alveolar osteitis. Al-Sukhun 2011 · Al-Sukhun Jehad, Penttilä Heikki · Journal of the Irish Dental Association PMID:21413548 | 2011 | 1 | none stated | not extracted yet |
| A double-blind placebo-controlled comparison of a novel formulation of intravenous diclofenac and ketorolac for postoperative third molar extraction… Christensen 2011 · Christensen Kyle, Daniels Stephen, et al. · Anesthesia progress PMID:21679043 | 2011 | 1 | none stated | not extracted yet |
| A Randomized, Controlled, Dose-ranging Study Investigating Single Doses of GW406381, Naproxen Sodium, or Placebo in Patients With Acute Pain After… Varner 2009 · Varner Julie, Lomax Mark, et al. · The Clinical Journal of Pain DOI:10.1097/ajp.0b013e3181a085fa | 2009 | 1 | 1 | not extracted yet |
| A randomized, controlled, dose-ranging study investigating single doses of GW406381, naproxen sodium, or placebo in patients with acute pain after… Varner 2009 · Varner Julie, Lomax Mark, et al. · The Clinical journal of pain PMID:19692798 | 2009 | 1 | none stated | not extracted yet |
| A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain Moberly 2007 · Moberly James B., Xu Jianbo, et al. · Clinical Therapeutics DOI:10.1016/s0149-2918(07)80078-6 | 2007 | 1 | none stated | not extracted yet |
| MK-0703 (a Cyclooxygenase-2 inhibitor) in Acute Pain Associated with Dental Surgery: A Randomized, Double-Blind, Placebo- and Active… Schwartz 2007 · Schwartz Jules I, Kotey Paul N.-A, et al. · American Journal of Therapeutics DOI:10.1097/mjt.0b013e31802dfb62 | 2007 | 1 | 1 | not extracted yet |
| MK-0703 (a cyclooxygenase-2 inhibitor) in acute pain associated with dental surgery: a randomized, double-blind, placebo- and active… Schwartz 2007 · Schwartz Jules I, Kotey Paul N-A, et al. · American journal of therapeutics PMID:17303970 | 2007 | 1 | none stated | not extracted yet |
| A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain. Moberly 2007 · Moberly James B, Xu Jianbo, et al. · Clinical therapeutics PMID:17577461 | 2007 | 1 | none stated | not extracted yet |
| Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: Results of two… Daniels 2006 · DANIELS S, DESJARDINS P, et al. · Clinical Therapeutics DOI:10.1016/j.clinthera.2006.07.005 | 2006 | 1 | 2 | not extracted yet |
| Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib… Hill 2006 · Michael Hill C., Sindet-Pederson Steen, et al. · Clinical Therapeutics DOI:10.1016/j.clinthera.2006.09.015 | 2006 | 1 | 1 | not extracted yet |
| Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two… Daniels 2006 · Daniels Stephen E, Desjardins Paul J, et al. · Clinical therapeutics PMID:16990080 | 2006 | 1 | none stated | not extracted yet |
| Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib… Hill 2006 · Michael Hill C, Sindet-Pederson Steen, et al. · Clinical therapeutics PMID:17062301 | 2006 | 1 | none stated | not extracted yet |
| Etoricoxib in acute pain associated with dental surgery: A randomized, double-blind, placebo- and active comparator-controlled dose-ranging study Malmstrom 2004a · Malmstrom Kerstin, Sapre Aditi, et al. · Clinical Therapeutics DOI:10.1016/s0149-2918(04)90067-7 | 2004 | 1 | 2 | not extracted yet |
| Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: A randomized, double-blind, placebo-controlled study in… Korn 2004 · Korn Scott, Vassil Theodore C, et al. · Clinical Therapeutics DOI:10.1016/s0149-2918(04)90076-8 | 2004 | 1 | 1 | not extracted yet |
| A Randomized, Double-Blind, Parallel-Group Study Comparing the Analgesic Effect of Etoricoxib to Placebo, Naproxen Sodium, and Acetaminophen With… Malmstrom 2004b · Malmstrom Kerstin, Kotey Paul, et al. · The Clinical Journal of Pain DOI:10.1097/00002508-200405000-00004 | 2004 | 1 | 2 | not extracted yet |
| The analgesic efficacy of intramuscular parecoxib sodium in postoperative dental pain Mehlisch 2004 · MEHLISCH D.R., DESJARDINS P.J., et al. · The Journal of the American Dental Association DOI:10.14219/jada.archive.2004.0085 | 2004 | 1 | 2 | not extracted yet |
| A randomized, double-blind, parallel-group study comparing the analgesic effect of etoricoxib to placebo, naproxen sodium, and acetaminophen with… Malmstrom 2004b · Malmstrom Kerstin, Kotey Paul, et al. · The Clinical journal of pain PMID:15100590 | 2004 | 1 | none stated | not extracted yet |
| Etoricoxib in acute pain associated with dental surgery: a randomized, double-blind, placebo- and active comparator-controlled dose-ranging study. Malmstrom 2004a · Malmstrom Kerstin, Sapre Aditi, et al. · Clinical therapeutics PMID:15220011 | 2004 | 1 | none stated | not extracted yet |
| Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: a randomized, double-blind, placebo-controlled study in… Korn 2004 · Korn Scott, Vassil Theodore C, et al. · Clinical therapeutics PMID:15220020 | 2004 | 1 | none stated | not extracted yet |
| The analgesic efficacy of intramuscular parecoxib sodium in postoperative dental pain. Mehlisch 2004 · Mehlisch D R, Desjardins P J, et al. · Journal of the American Dental Association (1939) PMID:15622663 | 2004 | 1 | none stated | not extracted yet |
| Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery Mehlisch 2003 · Mehlisch Donald R, Desjardins Paul J, et al. · Journal of Oral and Maxillofacial Surgery DOI:10.1016/s0278-2391(03)00315-x | 2003 | 1 | 2 | not extracted yet |
| Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery. Mehlisch 2003 · Mehlisch Donald R, Desjardins Paul J, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:12966478 | 2003 | 1 | none stated | not extracted yet |
| Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: A randomized,… Chang 2002 · Chang David J., Desjardins Paul J., et al. · Clinical Therapeutics DOI:10.1016/s0149-2918(02)85126-8 | 2002 | 1 | 2 | not extracted yet |
| Valdecoxib Is More Efficacious Than Rofecoxib in Relieving Pain Associated With Oral Surgery Fricke 2002 · Fricke James, Varkalis John, et al. · American Journal of Therapeutics DOI:10.1097/00045391-200203000-00003 | 2002 | 1 | 2 | not extracted yet |
| Valdecoxib is more efficacious than rofecoxib in relieving pain associated with oral surgery. Fricke 2002 · Fricke James, Varkalis John, et al. · American journal of therapeutics PMID:11897923 | 2002 | 1 | none stated | not extracted yet |
| Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: a randomized,… Chang 2002 · Chang David J, Desjardins Paul J, et al. · Clinical therapeutics PMID:12017395 | 2002 | 1 | none stated | not extracted yet |
| A double-blind, randomized comparison of intramuscularly and intravenously administered parecoxib sodium versus ketorolac and placebo in a… Daniels 2001 · Daniels S · Clinical Therapeutics DOI:10.1016/s0149-2918(01)80088-6 | 2001 | 1 | 2 | not extracted yet |
| A double-blind, randomized comparison of intramuscularly and intravenously administered parecoxib sodium versus ketorolac and placebo in a post-oral… Daniels 2001 · Daniels S E, Grossman E H, et al. · Clinical therapeutics PMID:11519767 | 2001 | 1 | none stated | not extracted yet |
| THE OPTIMAL ANALGESIC DOSE OF ROFECOXIB: OVERVIEW OF SIX RANDOMIZED CONTROLLED TRIALS Morrison 2000 · MORRISON BRIGGS W., FRICKE JAMES, et al. · The Journal of the American Dental Association DOI:10.14219/jada.archive.2000.0119 | 2000 | 1 | none stated | not extracted yet |
| The optimal analgesic dose of rofecoxib: Overview of six randomized controlled trials. Morrison 2000 · Morrison B W, Fricke J, et al. · Journal of the American Dental Association (1939) PMID:11143737 | 2000 | 1 | none stated | not extracted yet |
| A Randomized, Double‐Blind, Placebo‐Controlled, Dose‐Response Study of the Analgesic Effect of Lornoxicam After Surgical Removal of Mandibular Third… Norholt 1995 · Nørholt Sven E., Sindet‐Pedersen Steen, et al. · The Journal of Clinical Pharmacology DOI:10.1002/j.1552-4604.1995.tb05018.x | 1995 | 1 | 1 | not extracted yet |
| A randomized, double-blind, placebo-controlled, dose-response study of the analgesic effect of lornoxicam after surgical removal of mandibular third… Norholt 1995 · Nørholt S E, Sindet-Pedersen S, et al. · Journal of clinical pharmacology PMID:7665721 | 1995 | 1 | none stated | not extracted yet |
| Rangaswamy 2016 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Al-Sukhun 2011 matched by author and year (probable) | NR | 1 | 2 | not extracted yet |