Primary study · included by 1 review

Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: A randomized, placebo-controlled clinical trial

Chang 2002 · Chang David J., Desjardins Paul J., Chen Erluo, et al. · Clinical Therapeutics · 2002

Included by

Cyclooxygenase-2 selective inhibitors increase the risk of alveolar osteitis: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Chang 2002 · Reference [40]; Figures 1-2
Outcome this study informsPooled effectEvidenceCertainty
Alveolar osteitis (dry socket) occurrence
Diclofenac vs Placebo or untreated control
OR 1.83 [0.67, 5.04]3 studies · 641 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Rofecoxib vs Placebo or untreated control
OR 1.83 [1.05, 3.18]4 studies · 752 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Rofecoxib vs Placebo or untreated control
OR 1.59 [0.92, 2.77]4 studies · 824 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Rofecoxib vs Placebo or untreated control
OR 2.00 [1.18, 3.41]4 studies · 763 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Rofecoxib vs Placebo or untreated control
OR 1.89 [1.15, 3.10]5 studies · 947 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Rofecoxib vs Placebo or untreated control
OR 2.22 [1.21, 4.07]4 studies · 623 participantsGRADE not reported
Alveolar osteitis (dry socket)
COX-2 selective inhibitors, all drugs combined vs Placebo or untreated control
Overall results showed no statistical difference (no overall estimate reported)13 studies · 3820 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Rofecoxib vs Placebo or untreated control
OR 1.89 [1.11, 3.24]4 studies · 826 participantsGRADE not reported

1 including review in total.