Primary study · included by 1 review

Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery

Mehlisch 2003 · Mehlisch Donald R, Desjardins Paul J, Daniels Stephen, et al. · Journal of Oral and Maxillofacial Surgery · 2003

Included by

Cyclooxygenase-2 selective inhibitors increase the risk of alveolar osteitis: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Mehlisch 2003 · Reference [55]; Figures 1-2
Outcome this study informsPooled effectEvidenceCertainty
Alveolar osteitis (dry socket)
Traditional NSAIDs, all drugs combined vs Placebo or untreated control
The subgroup and the overall analyses showed no statistical difference in the risk of alveolar osteitis (no overall estimate reported)19 studies · 2888 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Ketorolac vs Placebo or untreated control
OR 1.53 [0.72, 3.24]4 studies · 397 participantsGRADE not reported
Alveolar osteitis (dry socket) occurrence
Parecoxib vs Placebo or untreated control
OR 1.75 [0.93, 3.27]3 studies · 962 participantsGRADE not reported

1 including review in total.