Primary study · included by 1 review

A double-blind, randomized comparison of intramuscularly and intravenously administered parecoxib sodium versus ketorolac and placebo in a postâoral surgery pain model

Daniels 2001 · Daniels S · Clinical Therapeutics · 2001

Included by

Cyclooxygenase-2 selective inhibitors increase the risk of alveolar osteitis: A systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Daniels 2001 · Reference [43]; Figures 1-2

Outcome this study informs	Pooled effect	Evidence	Certainty
Alveolar osteitis (dry socket) Traditional NSAIDs, all drugs combined vs Placebo or untreated control	The subgroup and the overall analyses showed no statistical difference in the risk of alveolar osteitis (no overall estimate reported)	19 studies · 2888 participants	GRADE not reported
Alveolar osteitis (dry socket) occurrence Ketorolac vs Placebo or untreated control	OR 1.53 [0.72, 3.24]	4 studies · 397 participants	GRADE not reported
Alveolar osteitis (dry socket) occurrence Parecoxib vs Placebo or untreated control	OR 1.75 [0.93, 3.27]	3 studies · 962 participants	GRADE not reported

1 including review in total.