Non-Cochrane · intervention · PM42293808

Clinical Efficacy of Cemented Versus Screw-Retained Zirconia Single Crowns: A Systematic Review and Meta-Analysis.

Mayta-Tovalino Frank, Espinoza-Carhuancho Fran, Alvitez-Temoche Daniel, et al. · International journal of dentistry · 2026 · PubMed · doi:10.1155/ijod/5497447

Findings

Population Adults with implant-supported zirconia single crowns

10 findings

Cemented zirconia single crownsScrew-retained zirconia single crownsMarginal bone level (MBL)
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
MD -0.04 [-0.08, -0.001]
-0.04 [-0.08, -0.001] mm
Moderate
Downgraded: risk of bias
8 studies · 298 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsMarginal bone level (MBL) change
Follow-up range 0.5 to 10 years · Follow-up duration (<5 vs >=5 years): subgroup reported significant, described as longer follow-up in the abstract
Unresolved: the two extractors disagree on this row.
MD -0.04 [-0.08, -0.00]
GRADE not reported
Studies not reported
Cemented zirconia single crownsScrew-retained zirconia single crownsModified plaque index (MPLI)
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
MD 5.01 [-7.05, 17.06]
5.01 [-7.05, 17.06] units
Moderate
Downgraded: risk of bias
2 studies · 57 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsFracture
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
RR 0.99 [0.82, 1.19]
487 per 1000 vs 482 per 1000
Low
Downgraded: risk of bias, imprecision
4 studies · 145 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsBleeding on probing (BoP)
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
MD 5.18 [-5.92, 16.29]
5.18 [-5.92, 16.29] %
Very low
Downgraded: risk of bias, imprecision, inconsistency
5 studies · 178 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsWidth of keratinized mucosa (KT)
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
MD -0.44 [-1.13, 0.26]
-0.44 [-1.13, 0.26] mm
Moderate
Downgraded: risk of bias
2 studies · 56 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsPlaque index (PI)
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
MD 0.01 [-0.13, 0.14]
0.01 [-0.13, 0.14] units
Low
Downgraded: risk of bias, imprecision
3 studies · 121 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsMarginal bone level (MBL) change
Follow-up range 0.5 to 10 years · Population type (adult, mixed, older): subgroup reported significant, described as adult populations in the abstract
Unresolved: the two extractors disagree on this row.
MD -0.04 [-0.08, -0.00]
GRADE not reported
Studies not reported
Cemented zirconia single crownsScrew-retained zirconia single crownsProbing depth (PD)
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
MD 0.03 [-0.16, 0.22]
0.03 [-0.16, 0.22] mm
Moderate
Downgraded: risk of bias
5 studies · 178 participants
Cemented zirconia single crownsScrew-retained zirconia single crownsScrew loosening
Follow-up range 0.5 to 10 years · Dental implant clinics (esthetic zone and posterior single-tooth gaps)
RR 0.94 [0.5, 1.77]
338 per 1000 vs 318 per 1000
Low
Downgraded: risk of bias, imprecision
3 studies · 119 participants

Included primary studies 9

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Amorfini 2018
Comparison of Cemented vs Screw-Retained, Customized Computer-Aided Design/Computer-Assisted Manufacture Zirconia Abutments for…
PMID:29624628
2018this review onlyMarginal bone level (MBL) change; Bleeding on probing (BoP); Plaque index (PI); Probing depth (PD)not extracted yet
Heierle 2019
Randomized Controlled Clinical Trial Comparing Cemented Versus Screw-Retained Single Crowns on Customized Zirconia Abutments: 3-Year…
PMID:30856641
2019this review onlyMarginal bone level (MBL) changenot extracted yet
Kraus 2019
Cemented vs screw-retained zirconia-based single implant reconstructions: A 3-year prospective randomized controlled clinical trial.
PMID:30861635
2019this review onlyMarginal bone level (MBL) change; Fracture; Screw looseningnot extracted yet
Kraus 2022
Five-year randomized controlled clinical study comparing cemented and screw-retained zirconia-based implant-supported single crowns.
PMID:35224774
2022this review onlyMarginal bone level (MBL) change; Bleeding on probing (BoP); Plaque index (PI); Probing depth (PD); Fracture; Screw looseningnot extracted yet
Kraus 2024
A 7.5-year randomized controlled clinical study comparing cemented and screw-retained one-piece zirconia-based implant-supported single…
PMID:39172056
2024this review onlyFracture; Screw looseningnot extracted yet
Lamperti 2022
Cemented versus screw-retained zirconia-based single-implant restorations: 5-year results of a randomized controlled clinical trial.
PMID:35051314
2022this review onlyMarginal bone level (MBL) change; Bleeding on probing (BoP); Probing depth (PD); Modified plaque index (MPLI); Width of keratinized mucosa (KT); Fracturenot extracted yet
Lv 2023
One-piece versus two-piece zirconia abutment supported single implant crown in the esthetic region: 3-Year results from a split-mouth…
PMID:37655630
2023this review onlyMarginal bone level (MBL) change; Bleeding on probing (BoP); Plaque index (PI); Probing depth (PD)not extracted yet
Thoma 2018
Randomized controlled clinical study of veneered zirconia abutments for single implant crowns: Clinical, histological, and microbiological…
PMID:30328283
2018this review onlyMarginal bone level (MBL) change; Bleeding on probing (BoP); Probing depth (PD); Modified plaque index (MPLI); Width of keratinized mucosa (KT)not extracted yet
Weigl 2019
Screw-retained monolithic zirconia vs. cemented porcelain-fused-to-metal implant crowns: a prospective randomized clinical trial in…
PMID:29946832
2019this review onlyMarginal bone level (MBL) changenot extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationAdults with implant-supported zirconia single crownsAdults with implant-supported zirconia single crowns, esthetic zone mostly (n=298)
InterventionCemented zirconia single crownsCemented zirconia single crowns
ComparisonScrew-retained zirconia single crownsScrew-retained zirconia single crowns
OutcomesPrimary: marginal bone level, bleeding on probing, plaque index; secondary: probing depth, modified plaque index, keratinized mucosa width, fracture, screw looseningMBL (8 RCTs), BoP (5), PI (3), PD (5), MPLI (2), KT (2), fracture (4), loosening (3)
Study designsRCTs9 RCTs
TimingFollow-up duration not restrictedFollow-up 6 months to 10 years

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalPartial YesPartial Yesyes
3Choice of study designs explainedYesNono
4Comprehensive literature searchcriticalPartial YesPartial Yesyes
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalNoNoyes
8Included studies described in detailYesYesyes
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: N/ANRSI: N/A · RCT: Yesno
10Funding of included studies reportedNoNoyes
11Appropriate meta-analysis methodscriticalRCT: Yes · NRSI: N/ANRSI: N/A · RCT: Yesno
12Impact of risk of bias on the pooled resultsNoNoyes
13Risk of bias accounted for in interpretationcriticalYesYesyes
14Heterogeneity explainedYesYesyes
15Publication bias investigatedcriticalNoNoyes
16Conflicts of interest reportedYesYesyes
OverallCritically LowCritically Lowyes