Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

129 questions · 295 findings · 29 reviews · Dental caries

No studies found 11 · 3.7%GRADE not reported 254 · 86.1%Very low 26 · 8.8%Low 3 · 1%Moderate 1 · 0.3%High 0 · 0%

Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns

Crown failure · Adults (18 years or older) needing a single crown in the molar or premolar region

It is very uncertain whether metal-free single crowns (full-contour zirconia) changes crown failure compared with cast gold (conventional metal) single crowns (very low certainty).

2 findings from 1 review

Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns

Crown complications · Adults (18 years or older) needing a single crown in the molar or premolar region

It is very uncertain whether metal-free single crowns (full-contour zirconia) changes crown complications compared with cast gold (conventional metal) single crowns (very low certainty).

2 findings from 1 review

Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns

Periodontal/peri-implant status and occlusal wear (secondary outcomes) · Adults (18 years or older) needing a single crown in the molar or premolar region

The review found no eligible studies for this question.

1 finding from 1 review

Single-surface ART restoration using high-viscosity glass ionomer vs No comparator

Restoration survival · Permanent posterior teeth with single-surface cavities

Single-surface high-viscosity glass-ionomer ART restorations in permanent teeth had high 2-year survival (93%, 95% CI 89-95%); evidence ungraded.

6 findings from 1 review
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Single-surface ART restoration using high-viscosity glass ionomer vs No comparator

Restoration survival · Primary posterior teeth with single-surface cavities

Single-surface high-viscosity glass-ionomer ART restorations in primary teeth had high 2-year survival (93%, 95% CI 91-94%); evidence ungraded.

3 findings from 1 review

Metal-free implant-supported single crowns (zirconia veneered with feldspathic ceramic) vs Metal-ceramic implant-supported single crowns

Marginal bone level (first bone to implant contact, FBIC) · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown

Metal-free implant-supported single crowns (zirconia veneered with… showed no clear difference in marginal bone level (first bone to implant contact, FBIC) compared with metal-ceramic implant-supported single crowns; GRADE not reported.

4 findings from 1 review
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Metal-free implant-supported single crowns (zirconia veneered with feldspathic ceramic) vs Metal-ceramic implant-supported single crowns

Patient satisfaction (measured by patient satisfaction or aesthetic scales) · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown

It is very uncertain whether metal-free implant-supported single crowns (zirconia veneered with… changes aesthetic evaluation (patient satisfaction VAS) compared with metal-ceramic implant-supported single crowns (very low certainty).

2 findings from 1 review

Metal-free implant-supported single crowns (zirconia veneered with feldspathic ceramic) vs Metal-ceramic implant-supported single crowns

Aesthetics · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown

It is very uncertain whether metal-free implant-supported single crowns (zirconia veneered with… changes aesthetic evaluation (pink and white aesthetic score, PES and WES… compared with metal-ceramic implant-supported single crowns (very low certainty).

1 finding from 1 review

Metal-free implant-supported single crowns (zirconia veneered with feldspathic ceramic) vs Metal-ceramic implant-supported single crowns

Implant crown failure · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown
1 finding from 1 review

Metal-free implant-supported single crowns (zirconia veneered with feldspathic ceramic) vs Metal-ceramic implant-supported single crowns

Implant crown complications · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown

It is very uncertain whether metal-free implant-supported single crowns (zirconia veneered with… changes implant crown complications compared with metal-ceramic implant-supported single crowns (very low certainty).

1 finding from 1 review

Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Early childhood caries (ECC) · Children aged 0-5 years in North Africa

Pooled ECC prevalence in Tunisia was 38% (95% CI 24-51), significantly lower than Egypt and Sudan.

10 findings from 1 review
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Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Dental caries prevalence · Primary school children in Ethiopia

Among studies using systematic random sampling, the pooled prevalence of dental caries was 35% (ungraded; CI not reported).

4 findings from 1 review
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Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Dental caries prevalence · Children (<18 years) with intellectual and developmental disabilities (IDD) in India

Dental caries affects about 64% of children with IDD in India (pooled prevalence 0.64, 95% CI 0.45-0.79; high heterogeneity; ungraded).

1 finding from 1 review

Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Periodontal disease prevalence · Children (<18 years) with intellectual and developmental disabilities (IDD) in India

In the single study reporting it, periodontal disease prevalence was 54.2% (single study; ungraded).

1 finding from 1 review

Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Early childhood caries experience (mean dmft) · Children younger than 71 months (under 6 years)

Mean dmft was lowest (1.62 teeth) in low-inequality countries by Gini index.

16 findings from 1 review
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Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Early childhood caries (ECC) · Children younger than 71 months (under 6 years)

Pooled ECC prevalence in Europe was 36% (95% CI 25-47).

16 findings from 1 review
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Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Regular toothbrushing usage (prevalence) · Children (<18 years) with intellectual and developmental disabilities (IDD) in India

About 91% of children with IDD in India use a toothbrush regularly (pooled prevalence 0.91, 95% CI 0.80-0.96; high heterogeneity; ungraded).

1 finding from 1 review

Not applicable (single-group prevalence) vs Not applicable (single-group prevalence)

Proportion of ancient skulls with at least one non-carious cervical lesion (NCCL) · Ancient/prehistoric human skulls (excavated/archaeological skeletal remains)

About 1.4% of ancient skulls (pooled) had at least one NCCL; crude 17/805 (2.11%) across 6 studies (ungraded, substantial heterogeneity I2=69%).

1 finding from 1 review