Findings

What do systematic reviews say?

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

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No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis · Mycological cure (short term; 5 to 15 days)
  Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
  OR 1.24 [1.03, 1.5]
  19 studies · 3057 participants
  Moderate
Direct match · question page
- Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis · Clinical cure (short term: 5 to 15 days)
  Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
  OR 1.14 [0.91, 1.43]
  13 studies · 1859 participants
  Moderate
Direct match · question page
- Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis · Side effects (patient‐reported side effects)
  Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
  OR 1.04
  16 studies · 3155 participants
  Low
Direct match · question page
- Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis · Time to first relief of symptoms
  Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1910 participants
  Low
Direct match · question page
- Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis · Safety (withdrawals due to adverse effects)
  Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  23 studies · 4637 participants
  High

Oral stimulation vs non‐oral intervention

Time (days) to achieve exclusive oral feeding · preterm infants

1 finding from 1 review

Oral stimulation for promoting oral feeding in preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 574 participants
Very low

One oral healthcare intervention vs another oral healthcare intervention

Presence of oral disease · people with stroke

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving oral health in people after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One oral healthcare intervention vs another oral healthcare intervention

Stroke survivor and providers' knowledge and attitudes to oral health care · people with stroke

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving oral health in people after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs IV followed by oral (11 days) therapy

Fever clearance time · children with acute pyelonephritis

1 finding from 1 review

Antibiotics for acute pyelonephritis in children 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 808 participants
Moderate

Oral vs IV followed by oral (11 days) therapy

Renal parenchymal damage at 6 to 12 months: all included children with acute pyelonephritis DMSA scans · children with acute pyelonephritis

Oral showed no clear difference in renal parenchymal damage at 6 to 12 months: all included children… compared with IV followed by oral (11 days) therapy (moderate certainty).

1 finding from 1 review

Antibiotics for acute pyelonephritis in children 2014 · Cochrane Headline outcomes only
RR 0.82 [0.59, 1.12]
4 studies · 943 participants
Moderate

Oral vs IV followed by oral (11 days) therapy

Renal parenchymal damage at 6 to 12 months: children with renal parenchymal damage on initial DMSA · children with acute pyelonephritis

Oral showed no clear difference in renal parenchymal damage at 6 to 12 months: children with renal… compared with IV followed by oral (11 days) therapy (moderate certainty).

1 finding from 1 review

Antibiotics for acute pyelonephritis in children 2014 · Cochrane Headline outcomes only
RR 0.79 [0.61, 1.03]
4 studies · 681 participants
Moderate

Combined oral and intravenous vs oral or intravenous alone

Wound infection · colorectal surgery

Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).

2 findings from 1 review

Antimicrobial prophylaxis for colorectal surgery 2014 · Cochrane Headline outcomes only
RR 0.55 [0.43, 0.71]
15 studies · 2929 participants
High
Antimicrobial prophylaxis for colorectal surgery 2014 · Cochrane Headline outcomes only
RR 0.52 [0.35, 0.76]
9 studies · 1880 participants
High

Oral stimulation vs usual care

Time (days) to achieve exclusive oral feeding · preterm infants

1 finding from 1 review

Oral stimulation for promoting oral feeding in preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 292 participants
Very low

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Clinical cure · women aged 16 and over with uncomplicated vulvovaginal candidiasis

Oral showed no clear difference in clinical cure (short term: 5 to 15 days) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty).

2 findings from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
OR 1.14 [0.91, 1.43]
13 studies · 1859 participants
Moderate
Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
OR 1.07 [0.77, 1.5]
9 studies · 1042 participants
Moderate

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Mycological cure · women aged 16 and over with uncomplicated vulvovaginal candidiasis

Oral probably leads to higher mycological cure (short term; 5 to 15 days) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty).

2 findings from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
OR 1.24 [1.03, 1.5]
19 studies · 3057 participants
Moderate
Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
OR 1.29 [1.05, 1.6]
13 studies · 1661 participants
Moderate

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Withdrawals due to adverse outcomes · women aged 16 and over with uncomplicated vulvovaginal candidiasis

1 finding from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
no estimate extracted
23 studies · 4637 participants
High

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Side effects (patient‐reported side effects) · women aged 16 and over with uncomplicated vulvovaginal candidiasis

Oral may leads to higher side effects (patient‐reported side effects) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (low certainty).

1 finding from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
OR 1.04
16 studies · 3155 participants
Low

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Patient preference / acceptance of treatment · women aged 16 and over with uncomplicated vulvovaginal candidiasis

1 finding from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 2206 participants
Low

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Time to first relief of symptoms · women aged 16 and over with uncomplicated vulvovaginal candidiasis

1 finding from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1910 participants
Low

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Costs · women aged 16 and over with uncomplicated vulvovaginal candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs intramuscular vitamin B12

Serum vitamin B12 levels Normal value: > 300 pg/mL (> 221 pmol/L)

1 finding from 1 review

Oral vitamin B₁₂ versus intramuscular vitamin B₁₂ for vitamin B₁₂ deficiency 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 153 participants
Low

Oral vs intramuscular vitamin B12

Clinical signs and symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Oral vitamin B₁₂ versus intramuscular vitamin B₁₂ for vitamin B₁₂ deficiency 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs intramuscular vitamin B12

Adverse events

1 finding from 1 review

Oral vitamin B₁₂ versus intramuscular vitamin B₁₂ for vitamin B₁₂ deficiency 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
Very low

Oral vs intramuscular vitamin B12

Health‐related quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Oral vitamin B₁₂ versus intramuscular vitamin B₁₂ for vitamin B₁₂ deficiency 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs intramuscular vitamin B12

Acceptability

The review found no eligible studies for this question.

1 finding from 1 review

Oral vitamin B₁₂ versus intramuscular vitamin B₁₂ for vitamin B₁₂ deficiency 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found