Question · asked by 1 review

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis: Side effects (patient‐reported side effects)

Oral may leads to higher side effects (patient‐reported side effects) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis
Side effects (patient‐reported side effects) · women aged 16 and over with uncomplicated vulvovaginal candidiasis
Oral may leads to higher side effects (patient‐reported side effects) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (low certainty).
Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal… (2020) · Cochrane Headline outcomes only
OR 1.0416 studies · 3155 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis (thrush)
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.