Recurrence of symptomatic UTI: cotrimoxazole (1) versus cefprozil (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in recurrence of symptomatic UTI: cotrimoxazole (1) versus cefprozil (2) compared with antibiotic 2 (moderate certainty).
2 findings from 1 review
Microbial resistance to prophylactic drugs: nitrofurantoin (1) versus cotrimoxazole (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 probably leads to lower microbial resistance to prophylactic drugs: nitrofurantoin (1)… compared with antibiotic 2 (moderate certainty).
1 finding from 1 review
Adverse events: cotrimoxazole (1) versus cefprozil (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in adverse events: cotrimoxazole (1) versus cefprozil (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Adverse events: nitrofurantoin (1) versus trimethoprim (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 may leads to higher adverse events: nitrofurantoin (1) versus trimethoprim (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in recurrence of symptomatic UTI: cotrimoxazole (1) versus cefadroxil (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured after 4 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
It is very uncertain whether systemic antibiotics changes resolution of ear discharge ‐ measured after 4 weeks (4 weeks)… compared with no treatment or placebo on top of topical antibiotics (very low certainty).
2 findings from 1 review
Antibiotic resistance · people (any age) with active trachoma
The review found no eligible studies for this question.
1 finding from 1 review
Antibiotics for trachoma 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Appendectomy in the antibiotic group · adults with uncomplicated appendicitis
1 finding from 1 review
Adverse effects of antibiotics · prolonged wet cough in children
Antibiotics showed no clear difference in children experiencing adverse effects of antibiotics (e.g.… compared with placebo (low certainty).
1 finding from 1 review
Need for additional antibiotic therapy · women with management of intra‐amniotic infection
1 finding from 1 review
Need for additional antibiotic therapy · women with management of intra‐amniotic infection
1 finding from 1 review
Antibiotic resistance · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants experiencing shunt infection after administration of antibiotic prophylaxis · CSF‐shunt infections
Antibiotic prophylaxis may leads to lower number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (low certainty).
1 finding from 1 review
Number of participants experiencing shunt infection after administration of intravenous antibiotic prophylaxis · CSF‐shunt infections
Antibiotic prophylaxis may leads to lower number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (low certainty).
1 finding from 1 review
Number of participants experiencing shunt infection after administration of intrathecal antibiotic prophylaxis · CSF‐shunt infections
Antibiotic prophylaxis showed no clear difference in number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (low certainty).
1 finding from 1 review
Number of participants experiencing shunt infection after implantation of antibiotic impregnated catheters · CSF‐shunt infections
It is very uncertain whether antibiotic prophylaxis changes number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (very low certainty).
1 finding from 1 review
Need for additional antibiotic therapy · women with management of intra‐amniotic infection
1 finding from 1 review
Antibiotic resistance · people with bronchiectasis
14 days on/off antibiotic regimen showed no clear difference in antibiotic resistance compared with 28 days on/off antibiotic regimen (moderate certainty).
1 finding from 1 review
OR 1 [0.68, 1.48]
Studies not reported
Moderate
Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women
Antibiotics showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Antibiotics… compared with topical treatments (low certainty).
2 findings from 1 review
28‐day antibiotic‐free days · hospital‐acquired pneumonia
1 finding from 1 review