Cochrane · systematic review · CD012902
Route of antibiotic prophylaxis for prevention of cerebrospinal fluid‐shunt infection
Arts, SHHMJ, Boogaarts, HD, van Lindert, EJ · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Multiple Sclerosis and Rare Diseases of the CNSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotic prophylaxis versus no antibiotic prophylaxis / standard care for CSF‐shunt infections
Population: CSF‐shunt infections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of participants experiencing shunt infection after administration of antibiotic prophylaxis Antibiotic prophylaxis vs no antibiotic prophylaxis / standard care | RR 0.55 [0.36, 0.84] | 11 studies · 1109 participants | Low Downgraded: imprecision, indirectness |
Number of participants experiencing shunt infection after administration of intravenous antibiotic prophylaxis Antibiotic prophylaxis vs no antibiotic prophylaxis / standard care | RR 0.55 [0.33, 0.9] | 8 studies · 797 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Number of participants experiencing shunt infection after administration of intrathecal antibiotic prophylaxis Antibiotic prophylaxis vs no antibiotic prophylaxis / standard care | RR 0.73 [0.28, 1.93] | 2 studies · 202 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Number of participants experiencing shunt infection after implantation of antibiotic impregnated catheters Antibiotic prophylaxis vs no antibiotic prophylaxis / standard care | RR 0.36 [0.1, 1.24] | 1 study · 110 participants | Very low Downgraded: risk of bias, imprecision, indirectness |