Death at hospital discharge · neonates with clinical and microbiological features of bacterial meningitis
It is very uncertain whether adjunctive steroid changes all‐cause death until hospital discharge compared with placebo (very low certainty).
1 finding from 1 review
Developmental delay at ≥ 18 months · neonates with clinical and microbiological features of bacterial meningitis
Adjunctive steroid showed no clear difference in number of participants with developmental delay compared with placebo (low certainty).
1 finding from 1 review
Hearing loss · neonates with clinical and microbiological features of bacterial meningitis
Adjunctive steroid showed no clear difference in hearing loss at 2 years of age compared with placebo (low certainty).
2 findings from 1 review
Number and nature of adverse events secondary to corticosteroid use (hospital‐acquired infection) · individuals with influenza
It is very uncertain whether corticosteroid therapy changes number and nature of adverse events secondary to corticosteroid use… compared with no corticosteroid therapy (very low certainty).
1 finding from 1 review
Death at 1 month (adults) · patients with Pneumocystis jiroveci pneumonia and HIV infection
Adjunctive corticosteroids leads to lower death at 1 month (adults) compared with no such treatment (high certainty).
1 finding from 1 review
Death at 3 to 4 months (adults) · patients with Pneumocystis jiroveci pneumonia and HIV infection
Adjunctive corticosteroids leads to lower death at 3 to 4 months (adults) compared with no such treatment (high certainty).
1 finding from 1 review
Death in hospital; children · patients with Pneumocystis jiroveci pneumonia and HIV infection
Adjunctive corticosteroids showed no clear difference in death in hospital; children compared with no such treatment (moderate certainty).
1 finding from 1 review
Need for mechanical ventilation · patients with Pneumocystis jiroveci pneumonia and HIV infection
Adjunctive corticosteroids probably leads to lower need for mechanical ventilation at 1 month compared with no such treatment (moderate certainty).
1 finding from 1 review
All‐cause mortality Up to 28 days following admission · individuals with influenza
It is very uncertain whether corticosteroid therapy changes number of deaths at 30 days following admission (30‐day mortality)a compared with no corticosteroid therapy (very low certainty).
1 finding from 1 review
Incidence of admissions to the ICU · individuals with influenza
It is very uncertain whether corticosteroid therapy changes rate of admission to intensive care units compared with no corticosteroid therapy (very low certainty).
1 finding from 1 review
Incidence of mechanical ventilation · individuals with influenza
It is very uncertain whether corticosteroid therapy changes proportion of participants requiring mechanical ventilation compared with no corticosteroid therapy (very low certainty).
1 finding from 1 review
Outcomes* · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Complete resolution of endophthalmitis at 3 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
It is very uncertain whether combined steroid and antibiotic therapy changes complete resolution of endophthalmitis at 3 months' compared with antibiotics alone (very low certainty).
1 finding from 1 review
Visual acuity · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
Combined steroid and antibiotic therapy may leads to higher visual acuity 6/6 to 6/18 at 3 months' compared with antibiotics alone (low certainty).
2 findings from 1 review
Improvement in visual acuity at 3 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intraocular pressure ( · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
1 finding from 1 review
Adverse events at 3 to 12 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
Combined steroid and antibiotic therapy showed no clear difference in adverse events at 3 to 12 months' compared with antibiotics alone (low certainty).
1 finding from 1 review
Costs · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
All‐cause mortality · patients with managing pulmonary tuberculosis
The intervention showed no clear difference in all‐cause mortality (low certainty).
1 finding from 1 review
Intervention not reported
Sputum Conversion by 2 months · patients with managing pulmonary tuberculosis
The intervention may leads to higher sputum Conversion by 2 months (low certainty).
1 finding from 1 review