Cochrane · systematic review · CD006150
Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection
Ewald, H, Raatz, H, Boscacci, R, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 50%High 2 · 50%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Adjunctive corticosteroids versus no such treatment for Pneumocystis jiroveci pneumonia in patients with HIV infection
Population: patients with Pneumocystis jiroveci pneumonia and HIV infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death at 1 month (adults) Adjunctive corticosteroids vs no such treatment | RR 0.56 [0.32, 0.98] | 6 studies · 489 participants | High |
Death at 3 to 4 months (adults) Adjunctive corticosteroids vs no such treatment | RR 0.59 [0.41, 0.85] | 5 studies · 448 participants | High |
Death in hospital; children Adjunctive corticosteroids vs no such treatment | RR 0.81 [0.51, 1.29] | 1 study · 100 participants | Moderate Downgraded: imprecision |
Need for mechanical ventilation at 1 month Adjunctive corticosteroids vs no such treatment | RR 0.38 [0.2, 0.73] | 3 studies · 388 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |