Question · asked by 1 review

Adjunctive corticosteroids vs no such treatment: Need for mechanical ventilation

Population
patients with Pneumocystis jiroveci pneumonia and HIV infection
Intervention
Adjunctive corticosteroids
Comparison
no such treatment
Outcome
Need for mechanical ventilation

Adjunctive corticosteroids probably leads to lower need for mechanical ventilation at 1 month compared with no such treatment (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Adjunctive corticosteroids vs no such treatment
Need for mechanical ventilation at 1 month · patients with Pneumocystis jiroveci pneumonia and HIV infection
Adjunctive corticosteroids probably leads to lower need for mechanical ventilation at 1 month compared with no such treatment (moderate certainty).
Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection (2015) · Cochrane Headline outcomes only
RR 0.38 [0.2, 0.73]3 studies · 388 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.