Anatomic success, defined as patency to lacrimal irrigation · nasolacrimal duct obstruction
Mitomycin C dacryocystorhinostomy showed no clear difference in anatomic success, defined as patency to lacrimal irrigation compared with dacryocystorhinostomy alone (low certainty).
2 findings from 1 review
Overall survival number of dead patients · adults receiving treatment for follicular lymphoma
ACR showed no clear difference in overall survival number of dead patients compared with non‐ACR (moderate certainty).
1 finding from 1 review
Mortality at 3 years · adults receiving treatment for follicular lymphoma
ACR showed no clear difference in mortality at 3 years compared with non‐ACR (moderate certainty).
1 finding from 1 review
Overall response · adults receiving treatment for follicular lymphoma
ACR showed no clear difference in overall response compared with non‐ACR (moderate certainty).
1 finding from 1 review
Disease control number of patients with progression · adults receiving treatment for follicular lymphoma
ACR leads to lower disease control number of patients with progression compared with non‐ACR (high certainty).
1 finding from 1 review
Progression/relapse · adults receiving treatment for follicular lymphoma
ACR leads to lower progression/relapse at 3 years compared with non‐ACR (high certainty).
1 finding from 1 review
Grade 3 to 4 neutropenia · adults receiving treatment for follicular lymphoma
It is very uncertain whether ACR changes neutropenia grade 3‐4 compared with non‐ACR (very low certainty).
1 finding from 1 review
Cardiotoxicity ( · adults receiving treatment for follicular lymphoma
It is very uncertain whether ACR changes cardiotoxicity** compared with non‐ACR (very low certainty).
1 finding from 1 review
Severe exacerbations (requiring ED visits or systemic steroids, or both) Number of people having ≥ 1 exacerbations requiring an ED visit or systemic steroids, or both. Classification varied across studies. Weighted mean study duration: 35 weeks · adults and children with chronic asthma
Macrolides probably leads to lower severe exacerbations (requiring ED visits or systemic steroids, or… compared with placebo (moderate certainty).
1 finding from 1 review
Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis
Tacrolimus 0.1% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).
3 findings from 1 review
RR 3.09 [2.14, 4.45]
1 study · 371 participants
Moderate
RR 0.95 [0.78, 1.16]
1 study · 377 participants
Low
RR 1.32 [1.17, 1.49]
1 study · 972 participants
Moderate
Adverse effects ‐ burning · people with atopic dermatitis
Tacrolimus 0.1% probably leads to higher adverse effects: burning ‐ tacrolimus 0.1% versus hydrocortisone… compared with corticosteroids (moderate certainty).
3 findings from 1 review
RR 2.91 [1.6, 5.28]
1 study · 371 participants
Moderate
RR 4.59 [3.1, 6.78]
1 study · 377 participants
Moderate
RR 3.79 [2.99, 4.81]
1 study · 972 participants
Moderate
Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis
Tacrolimus 0.03% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).
4 findings from 1 review
RR 2.05 [1.36, 3.08]
1 study · 411 participants
Moderate
RR 2.58 [1.96, 3.38]
2 studies · 790 participants
Moderate
RR 0.45 [0.13, 1.57]
2 studies · 409 participants
Very low
Show 1 more finding
Adverse effects ‐ burning · people with atopic dermatitis
1 finding from 1 review
Participant's self‐assessment of global response of improvement: tacrolimus 0.03% 2x/day versus hydrocortisone acetate 1% 2x/day · people with atopic dermatitis
Tacrolimus 0.03% probably leads to higher participant's self‐assessment of global response of improvement:… compared with corticosteroids (moderate certainty).
1 finding from 1 review
Functional success, defined as the relief of epiphora · nasolacrimal duct obstruction
Mitomycin C dacryocystorhinostomy showed no clear difference in functional success, defined as the relief of epiphora compared with dacryocystorhinostomy alone (low certainty).
2 findings from 1 review
Ostium size on nasal endoscopy · nasolacrimal duct obstruction
Mitomycin C dacryocystorhinostomy showed no clear difference in ostium size on nasal endoscopy compared with dacryocystorhinostomy alone (low certainty).
2 findings from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Macrolide showed no clear difference in number of participants experiencing one or more exacerbations… compared with tetracycline (low certainty).
1 finding from 1 review
Physician's assessment of global response of improvement · people with atopic dermatitis
Tacrolimus 0.03% leads to lower physician's assessment of global response of improvement, clear or… compared with tacrolimus 0.1% (high certainty).
1 finding from 1 review
Adverse effects · people with atopic dermatitis
Tacrolimus 0.03% showed no clear difference in adverse effects compared with tacrolimus 0.1% (moderate certainty).
1 finding from 1 review
Re‐bleeding Bleeding after initial success in the intervention · acute bleeding gastric varices in people with portal hypertension
It is very uncertain whether cyanoacrylate 1 mL changes re‐bleeding Bleeding after initial success in the intervention compared with cyanoacrylate 0.5 mL (very low certainty).
1 finding from 1 review