Sensitivity for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, pooled sensitivity of radiographic detection for all (initial and advanced) occlusal caries was 36.0% (95% CI 20 to 56) (ungraded).
3 findings from 1 review
Sensitivity 36.0 [20, 56]
9 studies
GRADE not reported
Sensitivity 38.6 [25, 54]
14 studies
GRADE not reported
Sensitivity 39.7 [25, 56]
11 studies
GRADE not reported
Intervention not reported
Overall failure
1 finding from 1 review
no estimate extracted
2 studies
GRADE not reported
Caries increment in permanent teeth · Children or adolescents
The NMR reported a difference between fluoride in rinse and placebo at randomisation years 1954 to 1990; no GRADE assessment was reported.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Gestational age (preterm birth < 37 weeks) · pregnant women
Pregnant women with dental caries did not have a significantly increased risk of preterm birth (pooled OR 1.16, 95% CI 0.90 to 1.49; 5 studies; I2=35%); certainty of evidence not graded.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children or adolescents
The illustrative network meta-regression estimated an SMD for caries increment for fluoride in gel versus fluoride in dentifrice across randomization year; the review did not state whether the difference was significant and certainty was not graded.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children or adolescents
The illustrative network meta-regression estimated an SMD for caries increment for fluoride in rinse versus fluoride in dentifrice across randomization year; the review did not state whether the difference was significant and certainty was not graded.
1 finding from 1 review
All proximal carious lesions · Permanent molar surfaces in diagnostic accuracy studies (mostly in vitro; clinical)
Pooled specificity for radiographic detection of all proximal lesions was 0.900 (95% CI 0.87 to 0.92).
1 finding from 1 review
Intervention not reported
Between-trial variance (fluoride caries NMR)
1 finding from 1 review
Sensitivity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, pooled sensitivity of visual detection for advanced occlusal caries was 43.7% (95% CI 37 to 51) (ungraded).
3 findings from 1 review
Sensitivity 43.7 [37, 51]
50 studies
GRADE not reported
Sensitivity 64.6 [57, 71]
94 studies
GRADE not reported
Sensitivity 75.1 [70, 81]
55 studies
GRADE not reported
Arrest of advanced cavitated carious lesions on any coronal surface · Primary teeth with advanced cavitated carious lesions on any coronal surface
38% SDF solution biannually compared with 12% SDF solution biannually: RR 1.29 (95% CI 1.21 to 1.38); High certainty.
1 finding from 1 review
Caries increment in permanent teeth · Children or adolescents
The NMR reported a difference between fluoride in dentifrice and placebo at every displayed randomisation year; no GRADE assessment was reported.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Caries increment, surface index D(M)FS · Children or adolescents
The illustrative network meta-regression estimated an SMD for caries increment for fluoride in varnish versus fluoride in gel across randomization year; the review did not state whether the difference was significant and certainty was not graded.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children or adolescents
In the illustrative network meta-regression the SMD for caries increment differed between fluoride in gel and no treatment at every displayed randomization year; certainty was not graded.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children or adolescents
In the illustrative network meta-regression the SMD for caries increment differed between fluoride in varnish and no treatment at randomization years 1954 to 1990; certainty was not graded.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children or adolescents
In the illustrative network meta-regression the SMD for caries increment differed between fluoride in rinse and placebo at randomization years 1954 to 1990; certainty was not graded.
1 finding from 1 review
Dental caries · Adult participants in HDI-stratified study populations
The pooled mean DMFT across HDI-stratified study populations was 11.49.
1 finding from 1 review
Caries lesion arrestment · Children with dentin caries lesions in the outer half of dentin on occlusal surfaces of primary teeth
Resin sealing and conventional restorative treatment (resin composite) did not differ significantly for caries lesion arrestment in outer-half occlusal dentin caries of primary teeth (2 studies; low certainty).
1 finding from 1 review
Total lesion area divided by total surface area (visual) · Patients with early caries lesions in permanent teeth (non-fluoridated water area)
Adding CPP-ACP to fluorides did not significantly change the lesion-area outcome for smooth-surface early caries lesions versus fluorides alone; not GRADE-rated.
1 finding from 1 review
Caries increment in permanent teeth · Children or adolescents
The NMR reported a difference between fluoride in varnish and no treatment at randomisation years 1954 to 1990; no GRADE assessment was reported.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Caries increment, surface index D(M)FS · Children or adolescents
In the illustrative network meta-regression the SMD for caries increment differed between placebo and no treatment at randomization years 1970 to 1990; certainty was not graded.
1 finding from 1 review