Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

418 questions · 611 findings · 68 reviews

No studies found 88 · 14.4%GRADE not reported 237 · 38.8%Very low 74 · 12.1%Low 115 · 18.8%Moderate 87 · 14.2%High 10 · 1.6%

Early inhaled steroids (< 2 weeks) vs placebo (among all randomised)

Oxygen requirement at 36 weeks' postmenstrual age · very low birth weight preterm neonates

Early inhaled steroids (< 2 weeks) showed no clear difference in CLD at 36 weeks' PMA oxygen dependency at 36 weeks' PMA compared with placebo (among all randomised) (moderate certainty).

1 finding from 1 review

Early inhaled steroids (< 2 weeks) vs placebo (among all randomised)

Death by, or CLD at, 36 weeks' PMA Death or oxygen dependency at 36 weeks' PMA · very low birth weight preterm neonates

Early inhaled steroids (< 2 weeks) probably leads to lower death by, or CLD at, 36 weeks' PMA Death or oxygen dependency at 36… compared with placebo (among all randomised) (moderate certainty).

1 finding from 1 review

Early inhaled steroids (< 2 weeks) vs placebo (among survivors)

CLD at 36 weeks' PMA · very low birth weight preterm neonates

Early inhaled steroid (< 2 weeks) probably leads to lower CLD at 36 weeks' PMA compared with placebo (among survivors) (moderate certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in chronic lung disease (oxygen use at 28 days in survivors) compared with no supplementation (moderate certainty).

2 findings from 1 review

Vitamin A vs no supplementation

Death or chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A probably leads to lower death or chronic lung disease (oxygen use at 28 days) compared with no supplementation (moderate certainty).

2 findings from 1 review

Vitamin A vs no supplementation

Death before 36 weeks' postmenstrual age · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in death before 36 weeks' postmenstrual age compared with no supplementation (moderate certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Neurodevelopmental impairment at 18 to 22 months · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in neurodevelopmental impairment at 18 to 22 months compared with no supplementation (low certainty).

1 finding from 1 review

Populations in countries with a lower Human Development Index (high category, HDI <0.800) vs Populations in countries with a higher Human Development Index (very high, HDI >=0.800)

Caries experience (mean DMFT) · Adults aged 19-60 years

Pooled caries experience (DMFT) was similar in very-high-HDI and high-HDI countries, and meta-regression found no significant association between national HDI and DMFT; ungraded observational evidence with very high heterogeneity.

3 findings from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) probably leads to higher vaginal delivery not achieved within 24 hours compared with low‐dose oral misoprostol (moderate certainty).

1 finding from 1 review

Systemic corticosteroids plus intranasal steroid/mucolytic/decongestant vs no intervention

Psychophysical testing for recovery of sense of smell · adults with olfactory dysfunction for ≥ 4 weeks following COVID‐19 infection

It is very uncertain whether systemic corticosteroids plus intranasal… changes psychophysical testing for recovery of sense of smell compared with no intervention (very low certainty).

1 finding from 1 review

Palmitoylethanolamide and luteolin vs no intervention

Recovery of sense of smell (as · adults with olfactory dysfunction for ≥ 4 weeks following COVID‐19 infection

It is very uncertain whether palmitoylethanolamide and luteolin changes recovery of sense of smell (as compared with no intervention (very low certainty).

1 finding from 1 review

Surface‐modified vs standard catheter

Recovery of kidney function · AKI patients receiving CKRT

Surface‐modified showed no clear difference in recovery of kidney function compared with standard double‐lumen catheter with identical geometry and flow design (low certainty).

1 finding from 1 review

Discontinued intravenous (IV) oxytocin stimulation vs continued IV oxytocin stimulation

Apgar score less than 7 at 5 minutes · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…

Discontinued intravenous (IV) oxytocin stimulation may leads to lower apgar score at five minutes below seven compared with continued IV oxytocin stimulation (low certainty).

1 finding from 1 review