Early inhaled steroids (< 2 weeks) vs placebo (among all randomised): Death by, or CLD at, 36 weeks' PMA Death or oxygen dependency at 36 weeks' PMA
Early inhaled steroids (< 2 weeks) probably leads to lower death by, or CLD at, 36 weeks' PMA Death or oxygen dependency at 36… compared with placebo (among all randomised) (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Early inhaled steroids (< 2 weeks) vs placebo (among all randomised) Death by, or CLD at, 36 weeks' PMA Death or oxygen dependency at 36 weeks' PMA · very low birth weight preterm neonates Early inhaled steroids (< 2 weeks) probably leads to lower death by, or CLD at, 36 weeks' PMA Death or oxygen dependency at 36… compared with placebo (among all randomised) (moderate certainty). Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight… (2017) · Cochrane Headline outcomes only | RR 0.86 [0.75, 0.99] | 6 studies · 1285 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.