Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Intraperitoneal lidocaine instillation may leads to lower number of women requiring rescue medication compared with intramuscular morphine (low certainty).
1 finding from 1 review
RR 0.22 [0.09, 0.54]
Studies not reported
Low
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with cancer pain
Methadone may leads to higher participant‐reported pain intensity compared with morphine (low certainty).
1 finding from 1 review
Adverse events: appetite, thirst, somnolence · people with cancer pain
1 finding from 1 review
At least 30% reduction in pain · people with cancer pain
1 finding from 1 review
At least 50% reduction in pain · people with cancer pain
1 finding from 1 review
Pain no worse than mild at one or two weeks (or equivalent) · people with cancer pain
1 finding from 1 review
Patient Global Impression of Change much or very much improved · people with cancer pain
1 finding from 1 review
Serious adverse events (death) · people with cancer pain
1 finding from 1 review
Other adverse events · people with cancer pain
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Treatment withdrawal · people with cancer pain
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Up to 6 h · Laparoscopic abdominal surgery (morphine consumption)
1 finding from 1 review
Additional analgesia required (escape analgesia) · children undergoing surgery
Tramadol showed no clear difference in number of patients requiring rescue analgesia (PACU) compared with morphine (low certainty).
2 findings from 1 review
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of patients with postoperative nausea and vomiting (postoperative care unit) · children undergoing surgery
Nalbuphine showed no clear difference in number of patients with postoperative nausea and vomiting… compared with morphine (low certainty).
1 finding from 1 review
Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · children undergoing surgery
Nalbuphine showed no clear difference in number of patients with postoperative nausea and vomiting (24 hours… compared with morphine (low certainty).
1 finding from 1 review
Number of patients with moderate/severe pain (1 hour postoperatively) · children undergoing surgery
Nalbuphine showed no clear difference in number of patients with moderate/severe pain (1 hour postoperatively) compared with morphine (low certainty).
2 findings from 1 review
Number of patients with the need for rescue analgesia (12 hours postoperatively) · children undergoing surgery
Nalbuphine showed no clear difference in number of patients with the need for rescue analgesia (12 hours… compared with morphine (low certainty).
1 finding from 1 review