DMFT/DMFS index (dental caries experience) · People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users
Illicit drug use was associated with substantially higher odds of dental caries experience (DMFT) (pooled OR 4.11, 95% CI 2.07-8.15; 7 studies; high heterogeneity I2=90.5%; ungraded).
1 finding from 1 review
Periodontal disease · People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users
Illicit drug use was not significantly associated with periodontal disease (pooled OR 1.44, 95% CI 0.80-2.60; 5 studies; substantial heterogeneity I2=85%; ungraded).
1 finding from 1 review
Dental caries · Adult participants in 25 meta-regression studies
The unadjusted meta-regression coefficient for low socioeconomic status was 10.49365.
2 findings from 1 review
Marginal adaptation (clinically detectable deterioration) · People with permanent posterior teeth restored with class I or II direct restorations
At 60 months, marginal adaptation did not differ significantly between the composites (4 groups; ungraded).
5 findings from 1 review
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Dental caries · Adult participants in 25 meta-regression studies
The Model 1 adjusted meta-regression coefficient for quantitative HDI was -42.94101.
3 findings from 1 review
Meta-regression coefficient -42.94101
6 studies
GRADE not reported
Meta-regression coefficient 20.17878
25 studies
GRADE not reported
Meta-regression coefficient 6.901906
7 studies
GRADE not reported
Secondary caries · People with permanent posterior teeth restored with class I or II direct restorations
No secondary caries was reported at 24 months in any of seven studies, so no meta-analysis was possible (ungraded).
2 findings from 1 review
Marginal discoloration · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, marginal discoloration did not differ significantly (7 groups; p = 0.77; ungraded).
4 findings from 1 review
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Dental caries · Adult participants in 25 meta-regression studies
The unadjusted meta-regression coefficient for older mean age was 4.324884.
2 findings from 1 review
Retention (restoration loss) · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, retention did not differ significantly between the composites (6 studies; ungraded).
2 findings from 1 review
Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations
Postoperative sensitivity at 12 months did not differ significantly between low polymerization shrinkage and methacrylate composites (OR 1.65, 95% CI 0.71 to 3.81; Moderate certainty).
2 findings from 1 review
Dental caries · Adult participants in 25 meta-regression studies
The Model 1 adjusted meta-regression coefficient for lower university education was -4.132903.
2 findings from 1 review
Death · Patients with severe malaria
In the illustrative network meta-regression no difference in the log odds ratio for death between artesunate and artemether was seen at any displayed average age; certainty was not graded.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Dental caries · Adult participants in 25 meta-regression studies
The unadjusted meta-regression coefficient for low schooling was -2.301079.
2 findings from 1 review
Plaque control · Children or adolescents
One RCT reported superior plaque control with a gamified mobile health app versus a conventional method; no effect estimate or GRADE assessment was reported.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with severely decayed maxillary primary incisors treated by pulpectomy (non-vital pulp therapy)
Composite strip crowns with composite posts had a low annual failure rate (2.3%) in maxillary primary incisors after pulpectomy (single high-risk-of-bias RCT; low quality of evidence; not GRADE-rated).
3 findings from 1 review
AFR 2.3
1 study · 54 participants
GRADE not reported
AFR 2.2
1 study · 54 participants
GRADE not reported
AFR 0
1 study · 54 participants
GRADE not reported
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Conventional GIC had an annual failure rate of 7.6-16.6% (2 RCTs) and failed more than amalgam in one trial; low quality of evidence (ungraded).
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; metal-reinforced GIC had the highest failure rate.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy)
Preformed metal crowns had a low annual failure rate (2.4%) in primary molars after pulpotomy, lower than amalgam in the same trial (single high-risk-of-bias RCT; low quality of evidence; not GRADE-rated).
2 findings from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
It is very uncertain whether selective carious tissue removal (selective excavation, SE) changes failure of therapy compared with hall Technique (sealing with a preformed metal crown) (very low certainty).
2 findings from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
Non-selective carious tissue removal and conventional restoration (CR) may leads to higher failure of therapy compared with hall Technique (sealing with a preformed metal crown) (low certainty).
1 finding from 1 review