Non-Cochrane · aetiology · PM32041585
Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis.
Yazdanian Mohsen, Armoon Bahram, Noroozi Alireza, et al. · BMC oral health · 2020 · PubMed · doi:10.1186/s12903-020-1010-3
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
2
current version
GRADE rated
0
No studies
0
Included studies
10
linked below
No studies 0 · 0%Ungraded 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | People who use drugs (PWUD): methamphetamine, heroin, opiate, cocaine, cannabis and crack users identified by self-report or interview | People who use drugs across 10 included studies (n=10); sample sizes 18-1015 |
| Intervention | Illicit drug use (methamphetamines, heroin, opiates, cocaine, cannabis, crack) | Specific drug types: methamphetamine, heroin, opiate/opioid, cannabis/marijuana, amphetamine, and mixed illicit drug use |
| Comparison | People who do not use drugs (PWDNUD) | People who do not use drugs |
| Outcomes | Oral health conditions: DMFT/DMFS (dental caries experience), periodontal disease, and tooth loss/edentulism (assessed individually) | Periodontal disease (5 studies); DMFT index (7 studies); tooth loss/edentulism not meta-analyzed |
| Study designs | Original cross-sectional and longitudinal (prospective/retrospective) observational studies (cohort, case-control, cross-sectional) comparing PWUD with non-users; qualitative, in vitro, animal studies, reviews, case reports/series, letters and congress abstracts excluded; quality assessed with JBI Critical Appraisal Checklist | 10 studies: 5 cross-sectional, 4 case-control, 1 cohort; JBI quality 6 high and 4 moderate |
| Timing | Not specified (studies published before 1 July 2019) | Included studies published 2007-2016 |
Search date: Before 1 July 2019. Databases: PsycINFO; PubMed; SciELO; Scopus; Web of Science; Cochrane Library
Questions and results
Illicit drug use vs People who do not use drugs
Population: People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Periodontal disease Illicit drug use was not significantly associated with periodontal disease (pooled OR 1.44, 95% CI 0.80-2.60; 5 studies; substantial heterogeneity I2=85%; ungraded). Source: Results 'Periodontal disease compared to drug type used'; Fig. 2 (forest plot); Fig. 3 (Begg's funnel plot) · same question in other reviews | OR 1.44 [0.80, 2.60] | 5 studies | Ungraded |
Illicit drug use vs People who do not use drugs
Population: People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
DMFT index (dental caries experience) Illicit drug use was associated with substantially higher odds of dental caries experience (DMFT) (pooled OR 4.11, 95% CI 2.07-8.15; 7 studies; high heterogeneity I2=90.5%; ungraded). Source: Results 'DMFT index compare to drug type used'; Fig. 4 (forest plot); Fig. 5 (Begg's funnel plot) · same question in other reviews | OR 4.11 [2.07, 8.15] | 7 studies | Ungraded |
Included primary studies 10
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| D'Amore et al. 2011 Oral health of substance-dependent individuals: impact of specific substances. PMID:21474269 | this review only | not stated | not extracted yet | not extracted yet |
| Gupta et al. 2012 Oral health status of a group of illicit drug users in Delhi, India. PMID:22482250 | this review only | not stated | not extracted yet | not extracted yet |
| Kayal et al. 2014 Illicit drug abuse affects periodontal health status. PMID:25028230 | this review only | not stated | not extracted yet | not extracted yet |
| Morio et al. 2008 Comparing diet, oral hygiene and caries status of adult methamphetamine users and nonusers: a pilot study. PMID:18245685 | this review only | not stated | not extracted yet | not extracted yet |
| Nives Protrka et al. 2013 Caries prevalence in heroin addicts. PMID:24696992 | this review only | not stated | not extracted yet | not extracted yet |
| Reece 2007 Dentition of addiction in Queensland: poor dental status and major contributing drugs. PMID:17687962 | this review only | not stated | not extracted yet | not extracted yet |
| Rommel et al. 2016 The impact of the new scene drug "crystal meth" on oral health: a case-control study. PMID:26174081 | this review only | not stated | not extracted yet | not extracted yet |
| Rooban et al. 2008 Dental and oral health status in drug abusers in Chennai, India: A cross-sectional study DOI:10.4103/0973-029x.42191 | this review only | not stated | not extracted yet | not extracted yet |
| Shetty et al. 2016 Methamphetamine Users Have Increased Dental Disease: A Propensity Score Analysis. PMID:26994107 | this review only | not stated | not extracted yet | not extracted yet |
| Thomson et al. 2008 Cannabis smoking and periodontal disease among young adults. PMID:18252882 | this review only | not stated | not extracted yet | not extracted yet |