Topic in Oral Health
Periodontology
Gingivitis, periodontitis, and plaque control, including oral hygiene devices and adjunctive therapies.
32 systematic reviews in Periodontology ask 793 questions. 18.7% have no studies to answer them, 17.3% rest on very low certainty evidence and 3.3% reach moderate or high certainty.
Reviews
32
Questions
793
current versions
No studies
18.7%
Moderate or high
3.3%
No studies 148 · 18.7%Ungraded 429 · 54.1%Very low 137 · 17.3%Low 53 · 6.7%Moderate 14 · 1.8%High 12 · 1.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT Patient satisfaction · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | No studies reported data for this outcome. | NR | No studies |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT Quality of life · Adults (> 18 years) with peri-implant mucositis, receiving active treatment Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies… | NR | No studies |
Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling Swelling at 24 hours · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement) · 24 hours Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (2024) · Cochrane | No data available for this outcome. | 0 studies | No studies |
Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics Pain at 24 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or… · 24 hours Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (2024) · Cochrane | MD -0.03 [-0.53, 0.47] | 2 studies · 61 participants | Very low |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT Change in gingival recession (REC) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | Only one study reported evidence for adjunctive aPDT in people with peri-implant disease (Al Rifaiy 2022). Data were only available for two outcomes (PPD and BOP), both reported only at three months. No studies… | NR | No studies |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT Change in clinical attachment level (CAL) · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care · 6 months (change from baseline) Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | MD 0.07 [-0.26, 0.40] | 2 studies · 85 participants | Very low |
Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics Swelling at 24 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or… · 24 hours Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (2024) · Cochrane | SMD 0.27 [-0.23, 0.78] | 2 studies · 62 participants | Very low |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT Change in probing pocket depth (PPD) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment · 6 months (change from baseline) Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | MD 0.52 [0.31, 0.74] | 15 studies · 452 participants | Very low |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT Outcome NR · Adults (> 18 years) with peri-implant mucositis, receiving supportive treatment Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | Planned comparison; no studies met the inclusion criteria. The review found only one study of peri-implant disease (peri-implant mucositis, active treatment) and no studies including people with peri-implantitis… | NR | No studies |
Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics Pain at 72 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or… · 72 hours Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (2024) · Cochrane | MD 0.08 [-0.38, 0.54] | 2 studies · 61 participants | Very low |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT Change in bleeding on probing (BOP) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment · 6 months (change from baseline) Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | MD 5.72 [1.62, 9.81] | 5 studies · 171 participants | Very low |
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT Outcome NR · Adults (> 18 years) with peri-implantitis, receiving active treatment Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases (2024) · Cochrane | Planned comparison; no studies met the inclusion criteria. The review found only one study of peri-implant disease (peri-implant mucositis, active treatment) and no studies including people with peri-implantitis… | NR | No studies |
Reviews 32
Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and dental disease and oral microbiota (part 1).
Non-Cochranefull textaetiology30 included studies
8 questions
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults
Cochranefull textintervention
26 questions
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases
Cochranefull textintervention
37 questions
Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and periodontal status in children and adolescents with nonsyndromic cleft lip and palate. Systematic literature review and meta-analysis.
Non-Cochranefull textaetiology24 included studies
8 questions
Association between periodontitis and dental caries: a systematic review and meta-analysis.
Non-Cochranefull textaetiology34 included studies
31 questions
Periodontitis and the risk of oral cancer: a meta-analysis of case-control studies.
Non-Cochranefull textaetiology16 included studies
11 questions
The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic treatment: a systematic review and meta-analysis.
Non-Cochranefull textintervention47 included studies
23 questions
White spot lesions, plaque accumulation and salivary caries-associated bacteria in clear aligners compared to fixed orthodontic treatment. A systematic review and meta- analysis.
Non-Cochranefull textintervention14 included studies
9 questions
Is there an association between periodontal disease and root caries? A systematic review and meta-analysis.
Non-Cochranefull textaetiology4 included studies
1 questions
Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults
Cochranefull textintervention
16 questions
Treatment of periodontitis for glycaemic control in people with diabetes mellitus
Cochranefull textintervention
10 questions
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis
Cochranefull textintervention
11 questions
A Systematic Review and Meta-Analysis of the Role of Sugar-Free Chewing Gum on Plaque Quantity in the Oral Cavity.
Non-Cochranefull textintervention8 included studies
4 questions
Effect of periodontal treatments on blood pressure
Cochranefull textintervention
49 questions
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis
Cochranefull textintervention
174 questions
Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis.
Non-Cochranefull textaetiology10 included studies
2 questions
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries
Cochranefull textintervention
60 questions
The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of chlorhexidine: a systematic review and meta-analysis.
Non-Cochranefull textintervention23 included studies
20 questions
Routine scale and polish for periodontal health in adults
Cochranefull textintervention
25 questions
Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis
Cochranefull textintervention
18 questions
Autologous platelet concentrates for treating periodontal infrabony defects
Cochranefull textintervention
34 questions
Treating periodontal disease for preventing adverse birth outcomes in pregnant women
Cochranefull textintervention
33 questions
Chlorhexidine mouthrinse as an adjunctive treatment for gingival health
Cochranefull textintervention
12 questions
Powered versus manual toothbrushing for oral health
Cochranefull textintervention
34 questions
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults
Cochranefull textintervention
16 questions